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[一例痛风患者并发肺炎球菌性关节炎]

[A case of pneumococcal arthritis in a patient with gout].

作者信息

Minoda S, Yamanouchi T, Ono Y, Kunii O, Akaoka I, Miyashita H

出版信息

Kansenshogaku Zasshi. 1989 Oct;63(10):1201-5. doi: 10.11150/kansenshogakuzasshi1970.63.1201.

Abstract

A 62 year-old man had suffered from gout and mild renal insufficiency since he was 40 years old. He was admitted to our hospital complicated by a productive cough, high fever and a right swollen knee joint. The chest radiographs demonstrated a left upper lobe infiltration shadow. Streptococci pneumoniae were found in the sputum, arterial blood and synovial fluid of the right knee joint, suggesting a severe pneumonia followed by pneumococcal septicemia which led to purulent arthritis. He was treated with cefamandole (CMD) and penicillin G (PC-G) for one week, but the chest X-ray findings were not improved. After treatment with cefbuperazone (CBPZ) and latamoxef (LMOX), his fever and other symptoms gradually resolved. Streptococcus pneumoniae is an uncommon organism of septic arthritis. Pneumococcal arthritis in a patient without immunodeficiency such as this case is very rare, and has not been reported in Japan.

摘要

一名62岁男性自40岁起患有痛风和轻度肾功能不全。他因咳嗽、高热和右膝关节肿胀而入住我院。胸部X光片显示左上叶浸润阴影。在痰液、动脉血和右膝关节滑液中发现肺炎链球菌,提示严重肺炎继发病原菌败血症并导致化脓性关节炎。他接受头孢孟多(CMD)和青霉素G(PC-G)治疗一周,但胸部X光检查结果未改善。使用头孢哌酮(CBPZ)和拉氧头孢(LMOX)治疗后,他的发热和其他症状逐渐缓解。肺炎链球菌是化脓性关节炎中一种不常见的病原体。像这种无免疫缺陷患者的肺炎球菌性关节炎非常罕见,在日本尚未见报道。

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