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甲苯咪唑治疗毛首鞭形线虫的有效性;2例轻度感染病例报告

Effectiveness of mebendazole in Trichuris trichiura; a report on 2 cases of mild infection.

作者信息

Ohnishi K, Ohyama T, Imagawa Y

出版信息

Kansenshogaku Zasshi. 1989 Jun;63(6):641-3. doi: 10.11150/kansenshogakuzasshi1970.63.641.

Abstract

Two admitted patients, a 5-year-old Filipino girl and a 29-year-old Indonesian man, who were diagnosed otherwise were concurrently found to harbour Trichuris trichiura eggs in stoll specimens containing 3,300 and 30 eggs per gram feces (EPG), respectively. A satisfactory response was obtained with administration of mebendazole in the recommended dose of 100 mg twice daily for three consecutive days. Repeated post-treatment fecal examinations revealed 0 EPG. Adverse reaction, either physical or laboratory, due to the anthelmintic was negative. The study indicates that the effectiveness of mebendazole on mild infection with T. trichiura is excellent without any untoward effect.

摘要

两名入院患者,一名5岁的菲律宾女孩和一名29岁的印度尼西亚男子,在被诊断为其他疾病的同时,粪便样本中分别被发现含有每克粪便3300个和30个鞭虫卵(EPG)。按照推荐剂量每日两次、每次100毫克连续服用三天甲苯达唑后,获得了满意的疗效。治疗后反复进行粪便检查显示每克粪便虫卵数为0。驱虫药引起的身体或实验室不良反应均为阴性。该研究表明,甲苯达唑对轻度鞭虫感染疗效极佳,且无任何不良影响。

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