Enokidani N
Kansenshogaku Zasshi. 1989 Jul;63(7):692-700. doi: 10.11150/kansenshogakuzasshi1970.63.692.
To determine normal proportions of pharyngeal H. influenzae and H. parainfluenzae, qualitative and quantitative mapping of the species in the pharynx of 538 healthy children was carried out. The detection rates of H. influenzae rose to a peak at 4, 5 years, with a slow decline thereafter. In contrast to H. influenzae, the detection rates of H. parainfluenzae rose as the child became older in age. The rates of H. influenzae and H. parainfluenzae of the total cultivable flora showed the same tendency as the detection rates. No consistent seasonal fluctuations was found with H. influenzae. The pharyngeal swab was inferior to the nasopharyngeal swab in each age group, for detecting the carriage of H. influenzae and H. parainfluenzae in the upper respiratory tract. The rate of ampicillin-resistant H. influenzae was 17.7% in the nasopharynx.
为确定咽部分离的流感嗜血杆菌和副流感嗜血杆菌的正常比例,对538名健康儿童咽部的这两种细菌进行了定性和定量定位研究。流感嗜血杆菌的检出率在4至5岁时达到峰值,此后缓慢下降。与流感嗜血杆菌不同,副流感嗜血杆菌的检出率随儿童年龄增长而上升。流感嗜血杆菌和副流感嗜血杆菌在可培养菌群中的比例与检出率呈现相同趋势。未发现流感嗜血杆菌有一致的季节性波动。在各年龄组中,咽拭子在检测上呼吸道流感嗜血杆菌和副流感嗜血杆菌携带情况方面不如鼻咽拭子。鼻咽部耐氨苄西林流感嗜血杆菌的比例为17.7%。