The Role of Medical Therapy for Variceal Bleeding.

作者信息

Bhutta Abdul Q, Garcia-Tsao Guadalupe

机构信息

Department of Internal Medicine, Yale University, 330 Cedar St, Boardman 110 P.O. Box 208056, New Haven, CT 06520-8056, USA; Section of Hospital Medicine, Yale-New Haven Hospital, 20 York Street, CB-2041, New Haven, CT 06520, USA.

Section of Digestive Diseases, Yale University School of Medicine, 333 Cedar St, 1080 LMP, P.O. Box 208019, New Haven, CT 06520-8019, USA; Section of Digestive Diseases, VA-CT Healthcare System, 950 Campbell Avenue, West Haven, CT 06516, USA.

出版信息

Gastrointest Endosc Clin N Am. 2015 Jul;25(3):479-90. doi: 10.1016/j.giec.2015.03.001. Epub 2015 Apr 20.

DOI:10.1016/j.giec.2015.03.001

PMID:26142033

Abstract

Acute variceal hemorrhage (AVH) is a lethal complication of portal hypertension and should be suspected in every patient with liver cirrhosis who presents with upper gastrointestinal bleed. AVH-related mortality has decreased in the last few decades from 40% to 15%-20% due to advances in the general and specific management of variceal hemorrhage. This review summarizes current management of AVH and prevention of recurrent hemorrhage with a focus on pharmacologic therapy.

摘要