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急诊胰腺手术——要求高且风险大。

Emergency pancreatic surgery--demanding and dangerous.

作者信息

Strobel Oliver, Schneider Lutz, Philipp Sebastian, Fritz Stefan, Büchler Markus W, Hackert Thilo

机构信息

Department of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

出版信息

Langenbecks Arch Surg. 2015 Oct;400(7):837-41. doi: 10.1007/s00423-015-1321-z. Epub 2015 Jul 7.

Abstract

BACKGROUND

Elective pancreatic surgery can be carried out with mortality rates below 5% in specialized centers today. Only few data exist on pancreatic resections in emergency situations. The aim of the study was to characterize indications, procedures, and outcome of emergency pancreatic surgery in a tertiary center.

METHODS

Prospectively collected data of all patients undergoing pancreatic operations at the authors' institution between October 2001 and December 2012 were analyzed regarding primary emergency operations in terms of indications, procedures, perioperative complications, and outcome. Emergency operations after preceding resections were excluded from the analysis.

RESULTS

Twenty-three emergency operations were performed during the observation period. Indications were duodenal perforation (n = 8), upper GI bleeding (n = 6), complicated pseudocysts (n = 3), bile duct perforation (n = 2), pancreatic bleeding after blunt abdominal trauma (n = 1), pancreatic stent perforation (n = 1), necrotizing cholecystitis (n = 1), and ileus (n = 1). Procedures included partial and total duodeno-pancreatectomy (n = 15), cystojejunostomy (n = 2), distal pancreatectomy (n = 4), reconstruction of the ampulla Vateri (n = 1), and duodenectomy (n = 1). Median intraoperative blood loss was 750 (200-2500) ml and OP time 4.25 (1.75-9.25) h. Mean ICU stay was 21.3 (1-80) days with an overall surgical morbidity of 52.2%. Overall in-hospital mortality was 34.8% (8/23 pat.).

CONCLUSIONS

Emergency pancreatic operations are infrequent and mainly performed due to duodenal perforation or bleeding; blunt abdominal trauma is rarely leading to emergency pancreas resections. They are associated with an increased morbidity and mortality and require a high level of surgical as well as interdisciplinary experience. Perioperative anesthesiological care and interventional radiological complication management are essential to improve outcome in this selective patient collective.

摘要

背景

如今在专业中心,择期胰腺手术的死亡率可低于5%。关于急诊情况下胰腺切除术的数据很少。本研究的目的是描述三级中心急诊胰腺手术的适应症、手术方式及结果。

方法

对2001年10月至2012年12月期间在作者所在机构接受胰腺手术的所有患者的前瞻性收集数据进行分析,内容包括初次急诊手术的适应症、手术方式、围手术期并发症及结果。分析排除了先前切除术后的急诊手术。

结果

观察期间共进行了23例急诊手术。适应症包括十二指肠穿孔(n = 8)、上消化道出血(n = 6)、复杂性假性囊肿(n = 3)、胆管穿孔(n = 2)、钝性腹部外伤后胰腺出血(n = 1)、胰腺支架穿孔(n = 1)、坏死性胆囊炎(n = 1)及肠梗阻(n = 1)。手术方式包括部分及全十二指肠胰切除术(n = 15)、囊肿空肠吻合术(n = 2)、胰体尾切除术(n = 4)、 Vater壶腹重建术(n = 1)及十二指肠切除术(n = 1)。术中中位失血量为750(200 - 2500)ml,手术时间为4.25(1.75 - 9.25)小时。平均重症监护病房停留时间为21.3(1 - 80)天,总体手术并发症发生率为52.2%。总体住院死亡率为34.8%(8/23例患者)。

结论

急诊胰腺手术不常见,主要因十二指肠穿孔或出血而进行;钝性腹部外伤很少导致急诊胰腺切除术。它们与发病率和死亡率增加相关,需要高水平的外科及多学科经验。围手术期麻醉护理及介入放射学并发症管理对于改善这一特定患者群体的结局至关重要。

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