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负面结果:负面认知限制了它们提高可重复性的潜力。

Negative results: negative perceptions limit their potential for increasing reproducibility.

作者信息

Teixeira da Silva Jaime A

机构信息

, P.O. Box 7, Miki-cho Post Office, Ikenobe 3011-2, Kagawa-ken, 761-0799, Japan.

出版信息

J Negat Results Biomed. 2015 Jul 7;14:12. doi: 10.1186/s12952-015-0033-9.

DOI:10.1186/s12952-015-0033-9
PMID:26149259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4494691/
Abstract

Negative results are an important building block in the development of scientific thought, primarily because most likely the vast majority of data is negative, i.e., there is not a favorable outcome. Only very limited data is positive, and that is what tends to get published, albeit alongside a sub-set of negative results to emphasize the positive nature of the positive results. Yet, not all negative results get published. Part of the problem lies with a traditional mind-set and rigid publishing frame-work that tends to view negative results in a negative light, or that only tends to reward scientists primarily for presenting positive findings. This opinion piece indicates that in addition to a deficient mind-set, there are also severe limitations in the availability of publishing channels where negative results could get published.

摘要

阴性结果是科学思维发展的重要基石,主要是因为极有可能绝大多数数据都是阴性的,也就是说,没有一个有利的结果。只有非常有限的数据是阳性的,而这往往会被发表,尽管会同时发表一部分阴性结果以强调阳性结果的积极性质。然而,并非所有阴性结果都会被发表。部分问题在于传统思维模式和僵化的出版框架,它们倾向于以负面眼光看待阴性结果,或者只倾向于主要奖励那些呈现阳性发现的科学家。这篇观点文章指出,除了思维模式的缺陷外,可供阴性结果发表的出版渠道也存在严重限制。

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本文引用的文献

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Reproducibility in science: improving the standard for basic and preclinical research.科学可重复性:提高基础和临床前研究的标准。
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Why is publication of negative clinical trial data important?为何公布阴性临床试验数据很重要?
Br J Pharmacol. 2012 Dec;167(7):1395-7. doi: 10.1111/j.1476-5381.2012.02215.x.
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Negative results: why do they need to be published?阴性结果:为何需要发表?
Int J Stroke. 2012 Jan;7(1):32-3. doi: 10.1111/j.1747-4949.2011.00723.x.
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Do pressures to publish increase scientists' bias? An empirical support from US States Data.发表压力会增加科学家的偏见吗?来自美国各州数据的实证支持。
PLoS One. 2010 Apr 21;5(4):e10271. doi: 10.1371/journal.pone.0010271.
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