Lang N, Favet L, Bodmer A
Rev Med Suisse. 2015 May 20;11(475):1138-40, 1142-3.
The incidence of breast cancer is rising up, but the mortality rate is decreasing, leading to a growing number of survivors. Most of these women are postmenopausal at diagnosis or will reach menopause following anti-cancer treatments. Most of them have hormone-sensitive tumors and will receive an anti-hormonal treatment. Endocrine therapy is associated with many adverse effects, including a worsening of climacteric symptoms with a negative impact on quality of life and therefore a suboptimal therapeutic adherence. Some supportive therapies can alleviate these adverse effects and should be offered to patients.
乳腺癌的发病率正在上升,但死亡率却在下降,这导致存活者的数量不断增加。这些女性中的大多数在确诊时已绝经,或者在接受抗癌治疗后会进入绝经期。她们中的大多数患有激素敏感性肿瘤,并将接受抗激素治疗。内分泌治疗会带来许多不良反应,包括更年期症状恶化,对生活质量产生负面影响,从而导致治疗依从性欠佳。一些支持性疗法可以减轻这些不良反应,应该提供给患者。