Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
作者信息
Strop Pavel, Delaria Kathy, Foletti Davide, Witt Jody Melton, Hasa-Moreno Adela, Poulsen Kris, Casas Meritxell Galindo, Dorywalska Magdalena, Farias Santiago, Pios Ariel, Lui Victor, Dushin Russell, Zhou Dahui, Navaratnam Thayalan, Tran Thomas-Toan, Sutton Janette, Lindquist Kevin C, Han Bora, Liu Shu-Hui, Shelton David L, Pons Jaume, Rajpal Arvind
机构信息
Rinat Laboratories, Pfizer Inc., South San Francisco, California, USA.
Worldwide Medicinal Chemistry, Pfizer Inc., Groton, Connecticut, USA.
出版信息
Nat Biotechnol. 2015 Jul;33(7):694-6. doi: 10.1038/nbt.3274.
DOI:10.1038/nbt.3274
PMID:26154005
Abstract
摘要
Zotero 插件