Torres M, Ercoreca L, Lucia J F, Giralt M, Raichs A
Thromb Haemost. 1979 Dec 21;42(4):1286-8.
In four healthy subjects with Factor XII levels equal to or below 50% (selected at random from 100 persons) the release of Kallikrein was studied in order to establish the relationship between the above data and those found in four Hageman trait carriers showing levels of Factor XII above the lowest normal limits. It was found that for similar amounts of Hageman activity three of the carriers showed significantly less release of Kallikrein than the control subjects in whom it was normal. The conclusion was reached that the additional determination of the amount of Kallikrein released may be of value in the detection of carriers of the Hageman trait.
在4名因子XII水平等于或低于50%(从100人中随机挑选)的健康受试者中,研究了激肽释放酶的释放情况,以确定上述数据与4名显示因子XII水平高于最低正常限度的哈格曼特性携带者的数据之间的关系。结果发现,对于相似量的哈格曼活性,三名携带者的激肽释放酶释放量明显低于激肽释放酶释放正常的对照受试者。得出的结论是,额外测定激肽释放酶的释放量可能对检测哈格曼特性携带者有价值。