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GEP-NETs 更新:分泌胃肠胰神经内分泌肿瘤和生物标志物。

GEP-NETs UPDATE: Secreting gastro-enteropancreatic neuroendocrine tumours and biomarkers.

机构信息

Departments of GastroenterologyClinical ChemistryMedical OncologyThe Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Departments of GastroenterologyClinical ChemistryMedical OncologyThe Netherlands Cancer Institute - Antoni van Leeuwenhoek, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

出版信息

Eur J Endocrinol. 2016 Jan;174(1):R1-7. doi: 10.1530/EJE-14-0971. Epub 2015 Jul 10.

Abstract

Neuroendocrine tumours (NETs) are rare tumours with an annual incidence in the population in a range of 2-5 new cases per 100,000 inhabitants. NETs are widely variable in terms of anatomical location, hormone production, clinical behaviour and syndromes they can cause. This article reviews the many localizations and clinical presentations of NETs with a main focus on clinical biomarkers and their use in medical practice.

摘要

神经内分泌肿瘤(NET)是一种罕见的肿瘤,其在人群中的年发病率为每 10 万人中有 2-5 例新发病例。NET 在解剖位置、激素产生、临床行为和可能引起的综合征方面存在广泛的差异。本文综述了 NET 的许多局部和临床表现,主要关注临床生物标志物及其在医学实践中的应用。

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