Joubert Christophe, Adetchessi Tarek, Peltier Emilie, Graillon Thomas, Dufour Henry, Blondel Benjamin, Fuentes Stephane
Department of Spine Surgery, Aix-Marseille University, Marseille, France; Department of Neurosurgery, Timone University Hospital, Marseille, France.
Department of Spine Surgery, Aix-Marseille University, Marseille, France; Department of Neurosurgery, Timone University Hospital, Marseille, France.
World Neurosurg. 2015 Nov;84(5):1412-22. doi: 10.1016/j.wneu.2015.06.072. Epub 2015 Jul 9.
Metastatic disease of the spine requires a multidisciplinary and comprehensive approach to patient care, especially, for patients in a lot of pain with neurological deficit or spinal instability requiring surgical stabilization.
The purpose of the study is to report our experience on 34 patients who underwent spinal metastasis resection. We used a single-stage posterior approach with vertebral body reconstruction by an expandable titanium cage and a posterior instrumentation. The parameters assessed were neurologic status, OMS score, angle of sagittal deformity, and morbidity.
Between January 2011 and June 2014 we performed a monocentric consecutive case review of 34 patients with vertebral body tumor. All of them underwent a single-stage vertebrectomy with circumferential reconstruction and an arthrodesis by posterior approach.
34 patients underwent a single stage surgery by posterior approach, including 30 thoracic lesions and 4 lumbar lesions. Pre operatively, sixteen patients presented a neurologic impairment. The mean follow-up was 13.7 months [1-32 m]. No neurologic impairment was observed in the 34 cases. At the last term of follow-up, neurologic status was improved in 23 cases. OMS score was improved in 23 cases (67.6 %), and worsened in one case. Before surgery, the average of visual analogic scale was 8.94/10 [7-10] and decreased to 2.62/10 [1-5] after surgery. Single posterior approach surgery significantly reduced the average sagittal deformity to 10.0° (0.01-19.96; P = 0.013, Mann-Whitney test).
Our outcomes suggest that it will be more efficient to perform an aggressive approach in spinal metastatic treatment in order to improve quality of life.
脊柱转移性疾病需要多学科综合治疗,特别是对于那些疼痛剧烈、伴有神经功能缺损或脊柱不稳定需要手术固定的患者。
本研究旨在报告我们对34例行脊柱转移瘤切除术患者的经验。我们采用单阶段后路手术,使用可扩张钛笼进行椎体重建并进行后路内固定。评估的参数包括神经功能状态、OMS评分、矢状面畸形角度和并发症。
2011年1月至2014年6月,我们对34例椎体肿瘤患者进行了单中心连续病例回顾。所有患者均接受单阶段后路椎体切除术、环形重建和后路融合术。
34例患者接受了后路单阶段手术,其中胸椎病变30例,腰椎病变4例。术前,16例患者存在神经功能损害。平均随访时间为13.7个月[1 - 32个月]。34例患者均未观察到神经功能损害。在最后一次随访时,23例患者的神经功能状态得到改善。23例患者(67.6%)的OMS评分得到改善,1例患者评分恶化。术前视觉模拟评分平均为8.94/10[7 - 10],术后降至2.62/10[1 - 5]。单后路手术显著将平均矢状面畸形减少至10.0°(0.01 - 19.96;P = 0.013,Mann - Whitney检验)。
我们的结果表明,在脊柱转移瘤治疗中采取积极的治疗方法以提高生活质量将更有效。