Chan Te-Fu, Tung Yi-Ching, Wang Shih-Han, Lee Chien-Hung, Lin Chih-Lung, Lu Peih-Ying
Department of Obstetrics and Gynecology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Public Health, School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Taiwan J Obstet Gynecol. 2015 Jun;54(3):270-4. doi: 10.1016/j.tjog.2013.06.021.
The aim of our study was to determine the relationship between age and the incidence of pre-eclampsia and eclampsia.
We analyzed data collected by the National Health Insurance Bureau between 1998 and 2010. Data were obtained from the Taiwanese Department of Health website and the Department of Internal Affairs.
The incidence of pre-eclampsia increased significantly (from 0.87% to 1.21%), but the incidence of eclampsia did not change significantly (from 0.04% to 0.05%) between 1998 and 2010. The incidence of pre-eclampsia in the 20-24-year age group was 0.60 ± 0.09%. The relative risk of pre-eclampsia in the different age groups was as follows: aged <20 years, 1.02-fold (p = 1.0); 25-29 years, 1.35-fold (p = 0.041); 30-34 years, 1.79-fold (p < 0.001); 35-39 years, 2.99-fold (p < 0.001); and ≥40 years, 5.13-fold (p < 0.001). The incidence of eclampsia in the 20-24-year age group was 0.04 ± 0.01%. The incidence of eclampsia in only the ≥40-years age group significantly increased by 2.49-fold (p = 0.001).
The incidence of pre-eclampsia was correlated with maternal age. The incidence of pre-eclampsia was the lowest in the 20-24-year age group and soared in the >35-year age groups.
我们研究的目的是确定年龄与先兆子痫和子痫发病率之间的关系。
我们分析了国民健康保险局在1998年至2010年期间收集的数据。数据取自台湾卫生署网站和内政部。
1998年至2010年期间,先兆子痫的发病率显著上升(从0.87%升至1.21%),但子痫的发病率没有显著变化(从0.04%升至0.05%)。20至24岁年龄组的先兆子痫发病率为0.60±0.09%。不同年龄组先兆子痫的相对风险如下:年龄<20岁,1.02倍(p = 1.0);25至29岁,1.35倍(p = 0.041);30至34岁,1.79倍(p < 0.001);35至39岁,2.99倍(p < 0.001);≥40岁,5.13倍(p < 0.001)。20至24岁年龄组的子痫发病率为0.04±0.01%。仅≥40岁年龄组的子痫发病率显著上升了2.49倍(p = 0.001)。
先兆子痫的发病率与产妇年龄相关。先兆子痫的发病率在20至24岁年龄组中最低,在>35岁年龄组中飙升。