McCunney Robert J, Morfeld Peter, Colby W David, Mundt Kenneth A
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge; Staff Physician, Brigham and Women's Hospital, Pulmonary Division, Boston, Germany, .
Noise Health. 2015 Jul-Aug;17(77):175-81. doi: 10.4103/1463-1741.160678.
Renewable energy demands have increased the need for new wind farms. In turn, concerns have been raised about potential adverse health effects on nearby residents. A case definition has been proposed to diagnose "Adverse Health Effects in the Environs of Industrial Wind Turbines" (AHE/IWT); initially in 2011 and then with an update in 2014. The authors invited commentary and in turn, we assessed its scientific merits by quantitatively evaluating its proposed application. We used binomial coefficients to quantitatively assess the potential of obtaining a diagnosis of AHE/IWT. We also reviewed the methodology and process of the development of the case definition by contrasting it with guidelines on case definition criteria of the USA Institute of Medicine. The case definition allows at least 3,264 and up to 400,000 possibilities for meeting second- and third-order criteria, once the limited first-order criteria are met. IOM guidelines for clinical case definitions were not followed. The case definition has virtually no specificity and lacks scientific support from peer-reviewed literature. If applied as proposed, its application will lead to substantial potential for false-positive assessments and missed diagnoses. Virtually any new illness that develops or any prevalent illness that worsens after the installation of wind turbines within 10 km of a residence could be considered AHE/IWT if the patient feels better away from home. The use of this case definition in the absence of a thorough medical evaluation with appropriate diagnostic studies poses risks to patients in that treatable disorders would be overlooked. The case definition has significant potential to mislead patients and its use cannot be recommended for application in any health-care or decision-making setting.
可再生能源需求的增长增加了对新风电场的需求。相应地,人们对其可能给附近居民带来的健康不利影响也日益担忧。已有人提出了一种病例定义,用于诊断“工业风力涡轮机周边地区的健康不利影响”(AHE/IWT);最初于2011年提出,随后在2014年进行了更新。作者邀请了各方发表评论,相应地,我们通过定量评估其拟议应用来评估其科学价值。我们使用二项式系数来定量评估获得AHE/IWT诊断的可能性。我们还通过将其与美国医学研究所病例定义标准指南进行对比,回顾了该病例定义的制定方法和过程。一旦满足有限的一级标准,该病例定义允许至少3264种、最多40万种满足二级和三级标准的可能性。该病例定义未遵循美国医学研究所临床病例定义指南。该病例定义几乎没有特异性,且缺乏同行评审文献的科学支持。如果按提议应用,其应用将导致大量假阳性评估和漏诊的可能性。实际上,在住宅10公里范围内安装风力涡轮机后出现的任何新发疾病或任何病情恶化的常见疾病,如果患者在离开家后感觉好转,都可能被视为AHE/IWT。在没有通过适当的诊断研究进行全面医学评估的情况下使用此病例定义会给患者带来风险,因为可治疗的疾病可能会被忽视。该病例定义极有可能误导患者,不建议在任何医疗保健或决策环境中使用。