Ye Xiaoming, Ni Kaiyuan, Zhou Xiaoshuai, Xie Kaigang, Hong Xiaoming
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yinzhou Second Hospital, Ningbo, China.
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yinzhou Second Hospital, Ningbo, China.
J Surg Res. 2015 Dec;199(2):402-6. doi: 10.1016/j.jss.2015.06.021. Epub 2015 Jun 16.
Partial hepatectomy is the most definitive treatment for hepatolithiasis. Laparoscopic liver resection, however, presents unique technical challenges. The objectives of this study were to evaluate and compare the safety and perioperative and long-term outcomes of laparoscopic left hemihepatectomy (LLH) versus open left hemihepatectomy (OLH) for left intrahepatic duct stones.
From March 2009-October 2014, 97 consecutive patients with left intrahepatic duct stones who underwent LLH (n = 46) or OLH (n = 51) were evaluated. We retrospectively reviewed the clinical outcomes and the stone clearance rates of the 97 patients in this study.
The median surgical procedure times were 254 min (188-396 min) in the LLH group and 236 min (192-395 min) in the OLH group. No significant difference was found in the surgical procedure times between the two groups. The intraoperative blood loss of the LLH group was less than the OLH group (332 mL [247-914 mL] versus 369 mL [221-996 mL], P = 0.13), but there was no statistical significance. A shorter length of postoperative hospital stay was noticed in laparoscopy group (11 d [8-21 d] versus 12 d [9-24 d], P = 0.01). Postoperative complications were observed in six of the 46 patients (13.0%) after LLH and in 11 of the 51 patients (21.6%) after OLH (P = 0.27). Laparoscopy was comparable with laparotomy in the effectiveness of stone clearance during the first attempt (93.5% versus 94.1%, P = 1.00).
In left-sided hepatolithiasis, LLH was safe and effective: it resulted in low postoperative morbidity, no mortality, and a high stone clearance rate. The potential benefit of LLH was a shorter hospital stay. If consideration is given to the appropriate indication criteria, including the extent of hepatectomy and the location and distribution of lesions, LLH may be an excellent choice for treatment of left-sided hepatolithiasis.
肝部分切除术是肝内胆管结石最确切的治疗方法。然而,腹腔镜肝切除术存在独特的技术挑战。本研究的目的是评估和比较腹腔镜左半肝切除术(LLH)与开放性左半肝切除术(OLH)治疗左肝内胆管结石的安全性、围手术期及长期疗效。
2009年3月至2014年10月,对97例连续接受LLH(n = 46)或OLH(n = 51)的左肝内胆管结石患者进行评估。我们回顾性分析了本研究中97例患者的临床结局和结石清除率。
LLH组手术时间中位数为254分钟(188 - 396分钟),OLH组为236分钟(192 - 395分钟)。两组手术时间差异无统计学意义。LLH组术中出血量少于OLH组(332毫升[247 - 914毫升]对369毫升[221 - 996毫升],P = 0.13),但无统计学意义。腹腔镜组术后住院时间较短(11天[8 - 21天]对12天[9 - 24天],P = 0.01)。LLH术后46例患者中有6例(13.0%)出现术后并发症,OLH术后51例患者中有11例(21.6%)出现术后并发症(P = 0.27)。首次尝试时,腹腔镜与开腹手术在结石清除效果方面相当(93.5%对94.1%,P = 1.00)。
对于左侧肝内胆管结石,LLH安全有效:术后发病率低,无死亡病例,结石清除率高。LLH的潜在益处是住院时间较短。如果考虑适当的适应证标准,包括肝切除范围、病变的位置和分布,LLH可能是治疗左侧肝内胆管结石的理想选择。