Whiteside Wendy, Pasquali Sara K, Yu Sunkyung, Bocks Martin L, Zampi Jeffrey D, Armstrong Aimee K
Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan C. S. Mott Children's Hospital, Ann Arbor, MI, USA.
The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2003, Cincinnati, OH, 45229-3039, USA.
Pediatr Cardiol. 2015 Dec;36(8):1754-60. doi: 10.1007/s00246-015-1230-5. Epub 2015 Jul 14.
The aim of this study was to determine the utility of intracardiac echocardiography (ICE) in assessing Melody™ transcatheter pulmonary valve (TPV) function immediately following valve implantation. ICE is used increasingly in percutaneous cardiac interventions. At our center, ICE is routinely utilized to evaluate valve function following Melody TPV implantation, but the utility of this practice remains unclear. A retrospective review of all Melody valves placed in the right ventricular outflow tract from April 2010 to September 2013 was performed. The clinical utility of ICE was described, along with the relationship between ICE data and traditional hemodynamic/angiographic data. ICE was performed in 54 cases and provided excellent Melody TPV visualization with no complications. ICE did not change clinical management but did provide supplemental information in two cases. In one case, angiography showed severe catheter-related Melody insufficiency. Subsequent ICE confirmed no insufficiency and prevented the need for additional angiography. In the second case, ICE allowed characterization of the mechanism of a residual gradient. ICE did not detect any clinically significant paravalvar leaks or valvar insufficiency not seen by angiography. The peak catheterization gradient was more closely approximated by the mean ICE gradient (median difference -7.4 % between measurements) than by the peak ICE gradient (median difference 58.3 %; p < 0.0001). ICE provides excellent and safe visualization following Melody TPV implantation but did not provide new clinical information impacting management in this series. Selective use of ICE in cases with more than expected valve insufficiency or larger than expected residual gradients may streamline use while maintaining optimal clinical outcomes.
本研究的目的是确定心腔内超声心动图(ICE)在评估Melody™经导管肺动脉瓣(TPV)植入后即刻瓣膜功能方面的效用。ICE在经皮心脏介入治疗中的应用越来越广泛。在我们中心,ICE常规用于评估Melody TPV植入后的瓣膜功能,但这种做法的效用仍不明确。对2010年4月至2013年9月期间植入右心室流出道的所有Melody瓣膜进行了回顾性研究。描述了ICE的临床效用,以及ICE数据与传统血流动力学/血管造影数据之间的关系。54例患者接受了ICE检查,ICE对Melody TPV的显示效果极佳,且无并发症发生。ICE未改变临床管理,但在2例患者中提供了补充信息。1例患者血管造影显示严重的导管相关Melody瓣关闭不全。随后的ICE证实无关闭不全,避免了进一步血管造影的必要。在第2例患者中,ICE有助于明确残余压差的机制。ICE未检测到血管造影未显示的任何具有临床意义的瓣周漏或瓣膜关闭不全。与ICE峰值压差(中位数差异58.3%;p<0.0001)相比,ICE平均压差与心导管检查峰值压差更为接近(测量值之间的中位数差异为-7.4%)。Melody TPV植入后,ICE能提供极佳且安全的图像显示,但在本系列研究中未提供影响管理的新临床信息。对于瓣膜关闭不全超过预期或残余压差大于预期的病例,选择性使用ICE可能在维持最佳临床结果的同时简化使用流程。