Lin Yu-Hsuan, Hu Chin, Chuang Hao-Wen, Lin Ming-Yee
Department of Otolaryngology, Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, R.O.C.
Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, R.O.C.
Oncol Lett. 2015 Jul;10(1):260-262. doi: 10.3892/ol.2015.3157. Epub 2015 Apr 28.
Actinomycosis is a chronic disease characterized by slow progression, abscess formation, tissue fibrosis and draining sinuses. Occurrence originating from the nasopharynx is extremely low. The present study described the case of a 46-year-old otherwise healthy female, with no remarkable history of mucosal injury or teeth rottenness, who presented with an asymptomatic nasopharyngeal mass that was detected incidentally by F-fluorodeoxyglucose positron emission tomography/computed tomography. A nasopharyngoscopy revealed an unclear demarcated granular mass. The patient then underwent a biopsy. Based on the obtained clinical images, microbiological results and histological findings, a diagnosis of actinomycosis was established. The patient experienced an uneventful eradication of the disease after two months of oral antibiotic treatment with amoxicillin. In conclusion, these findings indicate that actinomycosis should be included in the differential diagnosis of nasopharyngeal neoplasms.
放线菌病是一种慢性病,其特征为进展缓慢、形成脓肿、组织纤维化及有排脓窦道。起源于鼻咽部的病例极为罕见。本研究描述了一例46岁的健康女性,无明显黏膜损伤或龋齿病史,其通过氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描偶然发现了一个无症状的鼻咽部肿物。鼻咽镜检查显示肿物边界不清,呈颗粒状。患者随后接受了活检。根据获得的临床影像、微生物学结果及组织学发现,确诊为放线菌病。该患者口服阿莫西林进行抗生素治疗两个月后,疾病顺利治愈。总之,这些发现表明放线菌病应纳入鼻咽部肿瘤的鉴别诊断。