Choi Hayoung, Lee Hyun, Jeong Suk Hyeon, Um Sang-Won, Kown O Jung, Kim Hojoong
Department of Medicine, Samsung Medical Center, Division of Pulmonary and Critical Care Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Ann Thorac Med. 2017 Apr-Jun;12(2):121-124. doi: 10.4103/1817-1737.203752.
Pulmonary actinomycosis frequently mimics lung malignancy on radiologic imaging studies. Positron emission tomography-computed tomography (PET-CT) is a useful diagnostic modality for differentiating lung malignancy from benign diseases. However, few studies evaluated PET-CT findings of pulmonary actinomycosis. Therefore, it is unclear whether PET-CT is helpful to distinguish lung malignancy from benign lung disease when pulmonary actinomycosis is clinically suspected. We investigated PET-CT findings in 11 patients with pathologically confirmed pulmonary actinomycosis. The median maximal standardized uptake value (SUV) on PET-CT of pulmonary actinomycosis was increased to 5.5 (interquartile range, 4.2-8.8), which was higher than the threshold value of 2.5 indicating malignancy. Pulmonary actinomycosis without central necrosis demonstrated higher maximal SUV of 7.5 (4.9-12.2) compared to 4.8 (3.2-5.6) of ones with central necrosis. PET-CT might be not helpful in differentiating lung malignancy from benign lesions when pulmonary actinomycosis is clinically suspected.
在放射影像学研究中，肺放线菌病常酷似肺部恶性肿瘤。正电子发射断层扫描-计算机断层扫描（PET-CT）是鉴别肺部恶性肿瘤与良性疾病的一种有用的诊断方法。然而，很少有研究评估肺放线菌病的PET-CT表现。因此，当临床上怀疑肺放线菌病时，PET-CT是否有助于区分肺部恶性肿瘤与良性肺部疾病尚不清楚。我们调查了11例经病理证实的肺放线菌病患者的PET-CT表现。肺放线菌病PET-CT上的最大标准化摄取值（SUV）中位数增至5.5（四分位间距，4.2 - 8.8），高于提示恶性肿瘤的阈值2.5。无中央坏死的肺放线菌病最大SUV较高，为7.5（4.9 - 12.2），而有中央坏死的为4.8（3.2 - 5.6）。当临床上怀疑肺放线菌病时，PET-CT可能无助于区分肺部恶性肿瘤与良性病变。
