Cheng Ke-Jia, Wang Shen-Qing, Zhou Shui-Hong
Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China.
Oncol Lett. 2015 Jul;10(1):518-522. doi: 10.3892/ol.2015.3168. Epub 2015 Apr 30.
Inflammatory myofibroblastic tumors (IMTs) of the neck are rare, with only a few patients reported in the literature. The present study discusses the clinical manifestations, radiographic characteristics and management of these tumors, with a focus on imaging modalities. A case of IMT of the neck is presented and the associated literature is reviewed. In total, seven patients in seven English-language studies, including the present case, and one patient in one Chinese-language study were found. On CT scans, all tumors appeared as soft-tissue densities. Upon magnetic resonance imaging (MRI), all tumors displayed a heterogeneous hypointense-isointense signal on T1-weighted sequences and an isointense-hyperintense signal on T2-weighted sequences. All tumors showed enhancement on enhanced CT and MR images. The imaging features of the neck IMTs can be summarized as follows: i) When enhanced, the tumor displays enhancement on CT and MR images; ii) MRI is superior to CT scans in the differential diagnosis of this disease; iii) in general, the lesion displays a hypointense-isointense signal on T1-weighted sequences and an isointense-hyperintense signal on T2-weighted sequences; iv) due to the fibrous tissue in the tumor, delayed enhancement may be observed on gadolinium-enhanced MR images; and v) due to its benign or intermediate features, the tumor is usually a well-defined mass.
颈部炎性肌纤维母细胞瘤(IMTs)较为罕见,文献中仅报道了少数病例。本研究探讨了这些肿瘤的临床表现、影像学特征及治疗方法,重点关注成像方式。本文报告了1例颈部IMT病例,并对相关文献进行了综述。总共在7篇英文研究(包括本病例)中发现了7例患者,在1篇中文研究中发现了1例患者。在CT扫描中,所有肿瘤均表现为软组织密度。在磁共振成像(MRI)上,所有肿瘤在T1加权序列上均显示为不均匀的低信号-等信号,在T2加权序列上显示为等信号-高信号。所有肿瘤在增强CT和MR图像上均有强化。颈部IMT的影像学特征可总结如下:i)增强时,肿瘤在CT和MR图像上表现为强化;ii)在该疾病的鉴别诊断中,MRI优于CT扫描;iii)一般来说,病变在T1加权序列上表现为低信号-等信号,在T2加权序列上表现为等信号-高信号;iv)由于肿瘤内的纤维组织,钆增强MR图像上可能观察到延迟强化;v)由于其良性或中间特征,肿瘤通常为边界清晰的肿块。