Department of Head and Neck Surgery, Sun Yat-Sen University Cancer Center, No 651 Dongfeng East Road, Guangzhou, Guangdong, People's Republic of China.
Med Oncol. 2011 Dec;28 Suppl 1:S349-53. doi: 10.1007/s12032-010-9729-3. Epub 2010 Nov 2.
Inflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm. The aim of this study was to enhance the understanding of head and neck IMT and to improve its diagnosis and management. Clinical features and related treatment of 10 IMT cases were retrospectively analyzed and the literature was reviewed. Tumor sites identified included four in the maxillary space, two in the buccal space, two in the parotid gland, one in the post aurem, and one in the neck. Nine of ten patients received local resection, and one of ten patients received a total maxillectomy. One patient had a local recurrence and died, while the other nine patients had no distant metastases and survived. A computed tomography (CT) exam performed on nine of the ten patients showed that six of these nine cases were heterogeneous in density, while the other three cases were homogeneous. Four cases showed marked heterogeneous enhancement, two cases showed mild heterogeneous enhancement, and three cases showed moderate homogeneous enhancement on contrast-enhanced CT images. The incidence of IMT in the head and neck is low, and local resection is currently the best treatment. A prolonged postoperative follow-up period is necessary for patients with IMT.
炎性肌纤维母细胞瘤（IMT）是一种罕见的良性肿瘤。本研究旨在提高对头颈部 IMT 的认识，改善其诊断和治疗。回顾性分析了 10 例 IMT 患者的临床特征及相关治疗，并复习文献。肿瘤部位包括上颌窦 4 例、颊部 2 例、腮腺 2 例、耳后 1 例、颈部 1 例。10 例患者中 9 例接受局部切除术，10 例患者中 1 例接受全上颌骨切除术。1 例患者局部复发并死亡，其余 9 例患者无远处转移并存活。9 例患者中的 10 例行 CT 检查，其中 6 例密度不均匀，3 例密度均匀。4 例 CT 增强扫描表现为明显不均匀强化，2 例为轻度不均匀强化，3 例为中度均匀强化。头颈部 IMT 的发病率较低，目前局部切除术是最佳治疗方法。IMT 患者需要进行长期的术后随访。
