[帕金森病晚期提高生活质量的当前可能性]

[Current possibilities of quality of life improvement in the late stages of Parkinson's disease].

作者信息

Titova N V, Katunina E A

机构信息

Pirogov Russian Research Medical University, Moscow.

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(3):94-100. doi: 10.17116/jnevro20151153194-100.

DOI:10.17116/jnevro20151153194-100

PMID:26171484

Abstract

In this review, the authors describe the influence of Parkinson's disease on of the quality of life (QoL) of patients and highlight the importance of this parameter for assessment of treatment efficacy. Special attention is drawn to improvement of QoL in patients with resistant motor complications using invasive methods based on continuous dopaminergic stimulation. In the aspect of the influence on QoL, the main results of the studies of levodopa-carbidopa intestinal gel are reviewed.

摘要

在本综述中，作者描述了帕金森病对患者生活质量（QoL）的影响，并强调了该参数在评估治疗效果中的重要性。特别关注了使用基于持续多巴胺能刺激的侵入性方法改善有抵抗性运动并发症患者的生活质量。在对生活质量影响的方面，回顾了左旋多巴-卡比多巴肠凝胶研究的主要结果。