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2000-2013 年加拿大临床实践指南:加拿大萨斯喀彻温省骨密度筛查及其一致性:不变的风景。

Bone mineral density screening and its accordance with Canadian clinical practice guidelines from 2000-2013: an unchanging landscape in Saskatchewan, Canada.

机构信息

Faculty of Kinesiology and Health Studies, University of Regina, 3737 Wascana Pkwy, Regina, SK, S4S 0A2, Canada,

出版信息

Arch Osteoporos. 2015;10:227. doi: 10.1007/s11657-015-0227-2. Epub 2015 Jul 15.

Abstract

UNLABELLED

We examined the clinical characteristics of patients who underwent initial dual energy X-ray absorptiometry (DXA) testing at a primary care facility from 2000 to 2013, and whether these factors changed over time in accordance with Canadian clinical practice guidelines. The burden of osteoporosis remains high and largely unchanged and clinical practice guidelines are not being followed, overall.

PURPOSE

This study examined the clinical risk factors, therapeutic health behaviors, and bone mineral density (BMD) status of patients who underwent initial DXA testing at a primary care facility in Saskatchewan, Canada, and whether these factors changed over time from 2000 to 2013 in accordance with Canadian clinical practice guidelines.

METHODS

We conducted a retrospective cross-sectional medical chart audit of 800 patients 50 years of age and older who underwent their first DXA test to assess BMD status. Data was extracted from 2000 to 2013 and further stratified into four periods (2000-2001, 2002-2006, 2007-2009, and 2010-2013; n = 200 each period) based on the years when practice guidelines were implemented. Extracted data included BMD outcomes, clinical risk factor indicators for DXA testing, and recommendations for therapeutic health behaviors outlined in the clinical practice guidelines.

RESULTS

There were no differences in BMD status across the four time stratas (p = 0.430). Overall, most clinical risk factors had little change over time. The number of males screened significantly increased over time (p < 0.05), and osteoporosis drug therapy use decreased from 2000-2001 to 2010-2013 (p < 0.001). Increasing age, body mass <60 kg, and history of adult fracture were significant independent predictors of osteoporosis diagnosis.

CONCLUSIONS

The burden of osteoporosis remains high and largely unchanged in Saskatchewan, Canada. These results serve to inform strategies to enhance health-care provider awareness and compliance with practice guidelines, as well as improve screening rates and patient health behaviors.

摘要

目的

本研究调查了在加拿大萨斯喀彻温省一家初级保健机构进行首次双能 X 射线吸收法 (DXA) 检测的患者的临床危险因素、治疗健康行为和骨密度 (BMD) 状况,以及这些因素是否按照加拿大临床实践指南在 2000 年至 2013 年间随时间发生变化。

方法

我们对 800 名 50 岁及以上接受首次 DXA 检测以评估 BMD 状况的患者进行了回顾性横断面病历审核。数据从 2000 年至 2013 年提取,并根据实践指南实施的年份进一步分为四个时期(2000-2001 年、2002-2006 年、2007-2009 年和 2010-2013 年;每个时期 200 人)。提取的数据包括 BMD 结果、DXA 检测的临床危险因素指标以及临床实践指南中概述的治疗健康行为建议。

结果

四个时间分层的 BMD 状况没有差异(p=0.430)。总体而言,大多数临床危险因素随时间变化不大。接受筛查的男性人数显著增加(p<0.05),而骨质疏松症药物治疗的使用从 2000-2001 年降至 2010-2013 年(p<0.001)。年龄增长、体重<60kg 和成人骨折史是骨质疏松症诊断的显著独立预测因素。

结论

加拿大萨斯喀彻温省的骨质疏松症负担仍然很高且基本不变。这些结果为加强医疗保健提供者对实践指南的认识和遵守、提高筛查率和改善患者健康行为提供了信息。

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