Mishra Arvind, Singh Varun Kumar, Nanda Satyan
Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2015 Jul 14;2015:bcr2014209074. doi: 10.1136/bcr-2014-209074.
Rhabdomyolysis is a rare but potentially lethal complication of severe dengue fever. We present a case of 21-year-old man with fever, bodyache and black coloured and decreasing amount of urine. He was positive for NS1 (non-structural protein-1) antigen and IgM antibody for dengue. Platelet count was below 20 × 10(9)/L and kidney function test was deranged. Urine was positive for myoglobin. The patient was managed emergently on conservative lines and improved in 10 days. Rhabdomyolysis should always be kept in mind in a patient with severe dengue, as its early detection and prompt management can prevent further progression to acute renal failure.
横纹肌溶解是重症登革热一种罕见但可能致命的并发症。我们报告一例21岁男性患者,有发热、身体疼痛以及尿液颜色变黑且尿量减少的症状。他的登革热非结构蛋白1(NS1)抗原和IgM抗体检测呈阳性。血小板计数低于20×10⁹/L,肾功能检查结果异常。尿液肌红蛋白检测呈阳性。该患者接受了紧急保守治疗,并在10天内病情好转。对于重症登革热患者,应始终考虑到横纹肌溶解的可能,因为早期发现并及时处理可防止其进一步发展为急性肾衰竭。