Putri Anastasia, Arunsodsai Watcharee, Hattasingh Weerawan, Sirinam Salin
Thai Travel Clinic, Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Heliyon. 2024 Aug 22;10(17):e36379. doi: 10.1016/j.heliyon.2024.e36379. eCollection 2024 Sep 15.
Dengue infection is a well-known tropical disease that has become a global health issue. The clinical characteristics of dengue range from asymptomatic to severe, which can involve multiple organs and challenge management. Rhabdomyolysis in dengue infection is a rare condition described in children and adolescents. Herein, we present the case of a young adolescent with autism spectrum disorder who had a dengue virus serotype 1 infection complicated by rhabdomyolysis, which was not detected based on its typical manifestations. Rhabdomyolysis is recognized as one of the manifestations of expanded dengue syndrome and is associated with significant morbidity and mortality, especially if acute kidney injury develops. These coexisting conditions should be carefully considered, particularly in patients with underlying medical issues that may contribute to a worse prognosis. The early diagnosis and management of patients with dengue complicated by rhabdomyolysis is challenging and should be widely acknowledged. The detection of potential complications and appropriate fluid balance are essential to achieve a better prognosis.
登革热感染是一种广为人知的热带疾病，现已成为一个全球健康问题。登革热的临床特征从无症状到严重不等，可累及多个器官并给治疗带来挑战。登革热感染中的横纹肌溶解是一种在儿童和青少年中描述的罕见病症。在此，我们报告一例患有自闭症谱系障碍的青少年，其感染了1型登革热病毒并并发横纹肌溶解，基于其典型表现未被检测到。横纹肌溶解被认为是登革热综合征扩展的表现之一，与显著的发病率和死亡率相关，尤其是在发生急性肾损伤时。应仔细考虑这些共存情况，特别是在患有可能导致预后更差的基础疾病的患者中。登革热并发横纹肌溶解患者的早期诊断和治疗具有挑战性，应得到广泛认识。检测潜在并发症和维持适当的液体平衡对于实现更好的预后至关重要。
