Chachamovich Eduardo, Kirmayer Laurence J, Haggarty John M, Cargo Margaret, Mccormick Rod, Turecki Gustavo
Psychiatrist, McGill Group for Suicide Studies, Department of Psychiatry, McGill University, Montreal, Quebec; Assistant Professor, Department of Psychiatry, McGill University, Montreal, Quebec.
Psychiatrist, James McGill Professor, and Director, Division of Social and Transcultural Psychiatry, Department of Psychiatry, McGill University, Montreal, Quebec; Senior Investigator, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec.
Can J Psychiatry. 2015 Jun;60(6):268-75. doi: 10.1177/070674371506000605.
The Inuit population in Canada's North has suffered from high rates of death by suicide. We report on the first large-scale, controlled, epidemiologically representative study of deaths by suicide in an Indigenous population, which investigates risk factors for suicide among all Inuit across Nunavut who died by suicide during a 4-year period.
We identified all suicides by Inuit (n = 120) that occurred between January 1, 2003, and December 31, 2006, in Nunavut. For each subject, we selected a community-matched control subject. We used proxy-based procedures and conducted structured interviews with informants to obtain life histories, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Axis I and II diagnoses, and measures of impulsive and (or) aggressive traits.
Compared with control subjects, subjects who died by suicide were more likely to have experienced childhood abuse (OR 2.38; 95% CI 1.39 to 4.08), have family histories of major depressive disorder (P = 0.002) and suicide completion (P = 0.02), and have been affected by major depressive disorder (OR 13.00; 95% CI 6.20 to 27.25), alcohol dependence (OR 2.90; 95% CI 1.59 to 5.24), or cannabis dependence (OR 3.96; 95% CI 2.29 to 6.8) in the last 6 months. In addition, subjects who died by suicide were more likely to have been affected with cluster B personality disorders (OR 10.18; 95% CI 3.34 to 30.80) and had higher scores of impulsive and aggressive traits (P < 0.001).
At the individual level, clinical risk factors for suicide among Inuit are similar to those observed in studies with the general population, and indicate a need for improved access to mental health services. The high rate of mental health problems among control subjects suggests the need for population-level mental health promotion.
加拿大北部的因纽特人群自杀死亡率很高。我们报告了针对原住民人群自杀死亡情况的首个大规模、对照、具有流行病学代表性的研究,该研究调查了努纳武特地区所有在4年期间自杀死亡的因纽特人自杀的风险因素。
我们确定了2003年1月1日至2006年12月31日期间在努纳武特地区发生的所有因纽特人自杀事件(n = 120)。对于每个研究对象,我们选择了一个社区匹配的对照对象。我们采用基于代理人的程序,并对提供信息者进行结构化访谈,以获取生活史、《精神障碍诊断与统计手册》第四版轴I和轴II诊断结果,以及冲动和(或)攻击特质的测量结果。
与对照对象相比,自杀死亡的研究对象更有可能经历过童年虐待(比值比2.38;95%置信区间1.39至4.08),有重度抑郁症家族史(P = 0.002)和自杀既遂家族史(P = 0.02),并且在过去6个月内受到过重度抑郁症(比值比13.00;95%置信区间6.20至27.25)、酒精依赖(比值比2.90;95%置信区间1.59至5.24)或大麻依赖(比值比3.96;95%置信区间2.29至6.8)的影响。此外,自杀死亡的研究对象更有可能患有B类人格障碍(比值比10.18;95%置信区间3.34至30.80),并且冲动和攻击特质得分更高(P < 0.001)。
在个体层面,因纽特人自杀的临床风险因素与在普通人群研究中观察到的相似,这表明需要改善心理健康服务的可及性。对照对象中较高的心理健康问题发生率表明需要进行人群层面的心理健康促进。