三名造血干细胞移植患者中遗传性染色体整合人疱疹病毒6的病毒学分析
Virological analysis of inherited chromosomally integrated human herpesvirus-6 in three hematopoietic stem cell transplant patients.
作者信息
Miura H, Kawamura Y, Kudo K, Ihira M, Ohye T, Kurahashi H, Kawashima N, Miyamura K, Yoshida N, Kato K, Takahashi Y, Kojima S, Yoshikawa T
机构信息
Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Japan.
Faculty of Clinical Engineering, Fujita Health University School of Health Sciences, Toyoake, Japan.
出版信息
Transpl Infect Dis. 2015 Oct;17(5):728-31. doi: 10.1111/tid.12419. Epub 2015 Aug 22.
We analyzed 3 hematopoietic stem cell transplant (HSCT) recipients with inherited chromosomally integrated human herpesvirus-6 (inherited CIHHV-6). Cases 1 (inherited CIHHV-6A) and 2 (inherited CIHHV-6B) were inherited CIHHV-6 recipients. Case 3 received bone marrow from a donor with inherited CIHHV-6B. Following HSCT, HHV-6B was isolated from Case 1. HHV-6A and -6B messenger RNAs were detected in Cases 1 and 3.
我们分析了3例患有遗传性染色体整合型人疱疹病毒6型（遗传性CIHHV-6）的造血干细胞移植（HSCT）受者。病例1（遗传性CIHHV-6A）和病例2（遗传性CIHHV-6B）为遗传性CIHHV-6受者。病例3接受了来自患有遗传性CIHHV-6B供者的骨髓。HSCT后，从病例1中分离出HHV-6B。在病例1和病例3中检测到HHV-6A和-6B信使核糖核酸。
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