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先前经尿道前列腺电切术后,在前列腺尿道置入球囊导尿管行腹腔镜根治性前列腺切除术:配对分析的肿瘤学及功能学结果

Laparoscopic radical prostatectomy after previous transurethral resection of prostate using a catheter balloon inflated in prostatic urethra: Oncological and functional outcomes from a matched pair analysis.

作者信息

Pastore Antonio L, Palleschi Giovanni, Silvestri Luigi, Leto Antonino, Al-Rawashdah Samer F, Petrozza Vincenzo, Carbone Antonio

机构信息

Urology Unit, Department of Medico-Surgical Sciences and Biotechnologies, Faculty of Pharmacy and Medicine, ICOT, Sapienza University of Rome, Latina, Italy.

Uroresearch Association, Sapienza University of Rome, Latina, Italy.

出版信息

Int J Urol. 2015 Nov;22(11):1037-42. doi: 10.1111/iju.12869. Epub 2015 Jul 14.

Abstract

OBJECTIVES

To explore the surgical, oncological and functional outcomes of laparoscopic radical prostatectomy in patients who have undergone transurethral resection of the prostate, using a catheter balloon inflated in the prostatic urethra.

METHODS

A total of 25 patients were randomly assigned to the no balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy group (n = 12) and the with balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy group (n = 13). Two matched pairs analyses were carried out to identify the 12 (control A) and 13 (control B) surgery-naïve patients. The outcomes were compared between the groups with previous transurethral resection of the prostate (no balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy and with balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy groups) and the controls. The rate of intra- and postoperative complications was assessed. The International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form and the International Index of Erectile Function 5 were used for symptoms evaluation.

RESULTS

The mean blood loss was higher in patients submitted to transurethral resection of the prostate, with statistically insignificant reduced blood loss in the with balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy group. The no balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy group had longer operative time compared with both the with balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy and control A groups (P < 0.05). International Index of Erectile Function 5 showed a significant difference between no balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy and its control group; the International Consultation on Incontinence Questionnaire showed a statistically significant difference (P < 0.05) between the no balloon previous transurethral resection of the prostate laparoscopic radical prostatectomy and control A groups.

CONCLUSION

The use of a catheter balloon inflated in the prostatic urethra seems to facilitate laparoscopic radical prostatectomy in patients with previous transurethral resection of the prostate, ultimately reducing the rate of perioperative complications. These findings warrant further investigation on a larger case series with a longer follow up.

摘要

目的

探讨在接受过经尿道前列腺切除术的患者中,使用前列腺尿道内充气导管球囊进行腹腔镜前列腺癌根治术的手术、肿瘤学及功能学结局。

方法

总共25例患者被随机分配至未使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组(n = 12)和使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组(n = 13)。进行两组配对分析以确定12例(对照组A)和13例(对照组B)未接受过手术的患者。比较既往接受过经尿道前列腺切除术的两组(未使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组和使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组)与对照组的结局。评估术中和术后并发症发生率。使用国际尿失禁咨询委员会尿失禁简表和国际勃起功能指数5进行症状评估。

结果

接受经尿道前列腺切除术的患者平均失血量更高,使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组失血量减少,但差异无统计学意义。未使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组的手术时间比使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组和对照组A更长(P < 0.05)。国际勃起功能指数5显示,未使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组与其对照组之间存在显著差异;国际尿失禁咨询委员会问卷显示,未使用球囊的既往经尿道前列腺切除术腹腔镜前列腺癌根治术组与对照组A之间存在统计学显著差异(P < 0.05)。

结论

在前列腺尿道内充气的导管球囊似乎有助于既往接受过经尿道前列腺切除术的患者进行腹腔镜前列腺癌根治术,最终降低围手术期并发症发生率。这些发现值得在更大病例系列且随访时间更长的研究中进一步探讨。

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