Metsios George S, Stavropoulos-Kalinoglou Antonis, Kitas George D
c 3 Department of Physical Education and Sports Science, University of Thessaly, Thessaly, Greece.
b 2 Department of Rheumatology, Dudley Group NHS Foundation Trust, Russell's Hall Hospital, Dudley, West Midlands, UK.
Expert Rev Clin Immunol. 2015;11(10):1121-30. doi: 10.1586/1744666X.2015.1067606. Epub 2015 Jul 15.
Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with significant functional impairment and increased risk for cardiovascular disease. Along with pharmacological therapy, exercise seems to be a very promising intervention to improve disease-related outcomes, including functional ability and systemic manifestations, such as the increased cardiovascular risk. In this review, we discuss the physiological mechanisms by which exercise improves inflammation, cardiovascular risk and psychological health in patients with rheumatoid arthritis (RA) and describe in detail how exercise can be incorporated in the management of this disease using real examples from our clinical practice.
类风湿性关节炎（RA）是一种慢性炎症性疾病，与严重的功能障碍和心血管疾病风险增加相关。除药物治疗外，运动似乎是一种非常有前景的干预措施，可改善与疾病相关的结局，包括功能能力和全身表现，如心血管风险增加。在本综述中，我们讨论运动改善类风湿性关节炎（RA）患者炎症、心血管风险和心理健康的生理机制，并通过我们临床实践中的实例详细描述运动如何纳入该疾病的管理。
