Bahadir Ayse, Ortakoylu Mediha Gonenc, Iliaz Sinem, Kanmaz Zehra Dilek, Bagci Belma Akbaba, Iliaz Raim, Caglar Emel
Yedikule Education and Research Hospital for Chest Diseases and Thoracic Surgery, Istanbul, Turkey.
Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.
Geriatr Gerontol Int. 2016 Jul;16(7):791-6. doi: 10.1111/ggi.12549. Epub 2015 Jul 14.
The aim of the present study was to determine the prevalence of comorbidities in very elderly patients hospitalized as a result of acute respiratory diseases and to analyze sex-specific differences, and to examine the effects of these comorbidities on their treatment outcomes.
A total of 3316 patients were admitted to our pulmonary inpatient clinic between 2009 and 2011, and 243 of them (aged over 80 years) with acute respiratory disease were included in our study. Data were retrospectively collected, and included demographic features, comorbidities, laboratory findings, length of hospital stay and in-hospital mortality.
In total of 243, 144 patients (59.3%) were men and 99 patients (40.7%) were women. The mean age was 84 ± 3 years. The prevalence of comorbidity was 75.7% (n = 184). The most common comorbid disease in patients with chronic obstructive pulmonary disease was congestive heart failure (32.9%), and it was chronic obstructive pulmonary disease (49.4%) in patients with pneumonia. The rate of having one comorbidity was 58.2% (n = 107) and 35.3% (n = 65) had two. Approximately half (52.6%) of the in-hospital deaths occurred within the first 48 hours of hospitalization. The number of comorbidities was higher in the deceased patients compared with the living patients (P = 0.01).
The present study showed that the majority of our patients had at least one comorbidity. The first 48 hours of hospitalization was very important, especially for the patients with comorbidities, to determine the need for intensive care unit and prognosis. The coexistence of comorbidities can increase the risk of mortality in the elderly. Geriatr Gerontol Int 2016; 16: 791-796.
本研究旨在确定因急性呼吸道疾病住院的高龄患者中合并症的患病率，分析性别差异，并研究这些合并症对其治疗结果的影响。
2009年至2011年间，共有3316例患者入住我院肺病住院部，其中243例（年龄超过80岁）因急性呼吸道疾病纳入本研究。回顾性收集数据，包括人口统计学特征、合并症、实验室检查结果、住院时间和院内死亡率。
243例患者中，男性144例（59.3%），女性99例（40.7%）。平均年龄为84±3岁。合并症患病率为75.7%（n = 184）。慢性阻塞性肺疾病患者中最常见的合并症是充血性心力衰竭（32.9%），肺炎患者中最常见的合并症是慢性阻塞性肺疾病（49.4%）。合并一种合并症的比例为58.2%（n = 107），合并两种合并症的比例为35.3%（n = 65）。约一半（52.6%）的院内死亡发生在住院的前48小时内。死亡患者的合并症数量高于存活患者（P = 0.01）。
本研究表明，大多数患者至少有一种合并症。住院的前48小时非常重要，特别是对于合并症患者，以确定是否需要重症监护病房及预后。合并症的共存会增加老年人的死亡风险。《老年医学与老年病学国际杂志》2016年；16：791 - 796。
