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产后 4 年尿失禁和粪便失禁的频率、严重程度和危险因素:一项前瞻性队列研究。

Frequency, severity and risk factors for urinary and faecal incontinence at 4 years postpartum: a prospective cohort.

机构信息

Healthy Mothers Healthy Families Research Group, Murdoch Children's Research Institute, Melbourne, Vic., Australia.

Public Health, Epidemiology and Biostatistics, School of Health and Population Sciences, University of Birmingham, Birmingham, UK.

出版信息

BJOG. 2016 Jun;123(7):1203-11. doi: 10.1111/1471-0528.13522. Epub 2015 Jul 14.

Abstract

OBJECTIVES

To investigate frequency, severity and risk factors for urinary incontinence and faecal incontinence 4 years after a first birth.

DESIGN

Prospective pregnancy cohort study.

SETTING

Melbourne, Australia.

SAMPLE

A total of 1011 nulliparous women recruited in early pregnancy.

METHODS

Participants were followed up at 32 weeks of gestation; then at 3, 6, 9 and 12 months and 4 years postpartum.

MAIN OUTCOME MEASURES

Frequency and severity of urinary and faecal incontinence.

RESULTS

At 4 years, 29.6% of women reported urinary incontinence and 7.1% reported faecal incontinence. Compared with women having only spontaneous vaginal births, women who delivered exclusively by caesarean section were less likely to have urinary incontinence at 4 years postpartum (adjusted odds ratio 0.4, 95% confidence interval 0.3-0.6). Women who reported urinary incontinence before or during the index pregnancy, and those experiencing symptoms in the first year postpartum had increased odds of incontinence at 4 years, with the highest odds (6-12 times higher) among women who had previously reported moderate or severe symptoms. The odds of reporting faecal incontinence at 4 years were two to six times higher for women experiencing symptoms in pregnancy, and around four to eight times higher for those with symptoms in the first year postpartum.

CONCLUSION

Urinary and faecal incontinence are prevalent conditions 4 years after a first birth. Women reporting urinary or faecal incontinence during pregnancy had markedly higher odds of reporting symptoms at 4 years postpartum, suggesting a need for further investigation and elucidation of aetiological pathways involving nonbirth-related risk factors.

TWEETABLE ABSTRACT

Moderate/severe incontinence prevalent 4 years after first birth in population cohort. Prior symptoms are biggest predictor.

摘要

目的

调查初产妇产后 4 年时尿失禁和粪便失禁的频率、严重程度和危险因素。

设计

前瞻性妊娠队列研究。

地点

澳大利亚墨尔本。

样本

共招募了 1011 名初产妇。

方法

参与者在妊娠 32 周时进行随访;然后在产后 3、6、9 和 12 个月以及 4 年时进行随访。

主要观察指标

尿失禁和粪便失禁的频率和严重程度。

结果

在 4 年时,29.6%的女性报告有尿失禁,7.1%的女性报告有粪便失禁。与仅自然阴道分娩的女性相比,完全剖宫产分娩的女性产后 4 年发生尿失禁的可能性较低(校正优势比 0.4,95%置信区间 0.3-0.6)。在指数妊娠前或期间报告有尿失禁的女性,以及在产后第一年有症状的女性,在 4 年时发生尿失禁的可能性更高,其中报告有中度或重度症状的女性发生尿失禁的可能性最高(高 6-12 倍)。在妊娠期间有症状的女性报告粪便失禁的可能性是没有症状的女性的两到六倍,而在产后第一年有症状的女性报告粪便失禁的可能性是没有症状的女性的四到八倍。

结论

初产妇产后 4 年时尿失禁和粪便失禁是常见的疾病。在妊娠期间报告有尿失禁或粪便失禁的女性,在产后 4 年时报告有症状的可能性明显更高,这表明需要进一步调查和阐明与非分娩相关的危险因素涉及的病因途径。

推文摘要

初产妇产后 4 年时中度/重度尿失禁患病率高。既往症状是最大的预测因素。

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