在接受抗逆转录病毒治疗的HIV感染患者中使用苯达莫司汀治疗慢性淋巴细胞白血病：一例病例报告及文献综述

Treatment of chronic lymphocytic leukemia with bendamustine in an HIV-infected patient on antiretroviral therapy: a case report and review of the literature.

作者信息

Shimada Naoki, Yuji Koichiro, Ohno Nobuhiro, Koibuchi Tomohiko, Oyaizu Naoki, Uchimaru Kaoru, Tojo Arinobu

机构信息

Promotion Plan for the Platform of Human Resource Development for Cancer, Research Hospital, The Institute of Medical Science, The University of Tokyo Tokyo, Japan.

Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo Tokyo, Japan.

出版信息

Clin Case Rep. 2015 Jun;3(6):453-60. doi: 10.1002/ccr3.244. Epub 2015 Apr 22.

DOI:10.1002/ccr3.244

PMID:26185648

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4498862/

Abstract

Few reports have described the coincidence of chronic lymphocytic leukemia (CLL) and HIV. We administered bendamustine to an HIV-positive refractory CLL patient and obtained a significant objective response. Our results indicate that bendamustine can be used in HIV-infected CLL patients. We also reviewed 12 cases of CLL with HIV infection.

摘要

很少有报告描述过慢性淋巴细胞白血病（CLL）与HIV的巧合情况。我们对一名HIV阳性的难治性CLL患者给予了苯达莫司汀，并获得了显著的客观缓解。我们的结果表明苯达莫司汀可用于HIV感染的CLL患者。我们还回顾了12例合并HIV感染的CLL病例。