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黑猩猩指名亚种(Pan troglodytes troglodytes)的完整线粒体基因组。

The complete mitochondrial genome of the central chimpanzee, Pan troglodytes troglodytes.

作者信息

Liu Bang, Hu Xiao-di, Gao Li-Zhi

机构信息

a Medical Faculty, Kunming University of Science and Technology , Kunming , China and.

b Faculty of Life Science and Technology , Kunming University of Science and Technology , Kunming , China.

出版信息

Mitochondrial DNA A DNA Mapp Seq Anal. 2016 Jul;27(4):2775-6. doi: 10.3109/19401736.2015.1053060. Epub 2015 Jul 20.

Abstract

This study first report the complete mitochondrial genome sequence of the central chimpanzee, Pan troglodytes troglodytes. The genome was a total of 16 556 bp in length and had a base composition of A (31.05%), G (12.95%), C (30.84%), and T (25.16%), indicating that the percentage of A + T (56.21%) is higher than G + C (43.79%). Similar to other primates, it possessed a typically conserved structure, including 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes and 1 control region (D-loop). Most of these genes were found to locate on the H-strand except for the ND6 gene and 8 tRNA genes. The phylogenetic analysis showed that the P. t. troglodytes mitochondrial genome formed a cluster with the other three Pan troglodytes genomes and that the genus Pan is closely related to the genus Homo. This mitochondrial genome sequence would supply useful genetic resources to help the conservation management of primate germplasm and uncover hominoid evolution.

摘要

本研究首次报道了黑猩猩指名亚种(Pan troglodytes troglodytes)的完整线粒体基因组序列。该基因组全长16556bp,碱基组成为A(31.05%)、G(12.95%)、C(30.84%)和T(25.16%),表明A+T的百分比(56.21%)高于G+C(43.79%)。与其他灵长类动物相似,它具有典型的保守结构,包括13个蛋白质编码基因、22个转运RNA基因、2个核糖体RNA基因和1个控制区(D环)。除ND6基因和8个tRNA基因外,这些基因大多位于重链上。系统发育分析表明,黑猩猩指名亚种的线粒体基因组与其他三种黑猩猩基因组形成一个聚类,且黑猩猩属与人类属密切相关。该线粒体基因组序列将提供有用的遗传资源,以帮助灵长类种质的保护管理并揭示类人猿的进化。

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