Buonanno C, Dander B, Paris B, Vassanelli C, Del Giglio G, Reggio C, Poppi A
G Ital Cardiol. 1979;9(10):1177-83.
On the hypothesis that encroachment on left ventricular performance by postinfarction aneurysm (An) is related to its size, a method was investigated for the measurement of aneurysmal dimensions. On radioopaque plastic casts grossly ellipsoidal in shape with addition of masses in different position to simulate aneurysms, satisfactory data for volume calculation were obtained by the association of the ellipsoid formula applied to the contractile portion with the formula of the hemispheroid applied to the aneurysmal section, the difference between real and calculated volumes being not more than +/-5%. In 100 Pts. with previous myocardial infarction, showing at ventriculography akinetic-diskinetic segments of the left ventricular wall, the absolute volume of An and its percentage value of the total left ventricular volume (V An%) were measured. A statistical correlation was studied with other hemodynamic and angiographic parameters of left ventricular function. Cardiac index and angiographic stroke volume decreased with increasing V An%, but with a low correlation, of no statistical significance; only for An with a volume of 60% or more C.I. and SV were constantly reduced. The LVEDP, higher than normal in 80% of the cases, rose with increasing V An%, but with a correlation of low statistical significance. The EDV increased progressively and significatively with increasing V An%, resulting therefore in relation with the extension of noncontracting segment.
基于心肌梗死后室壁瘤(An)对左心室功能的影响与其大小有关这一假说,研究了一种测量室壁瘤大小的方法。在形状大致为椭圆形的不透X线塑料铸型上添加不同位置的团块以模拟室壁瘤,将适用于收缩部分的椭球体公式与适用于室壁瘤部分的半球体公式相结合,获得了令人满意的体积计算数据,实际体积与计算体积之间的差异不超过±5%。在100例有既往心肌梗死病史、心室造影显示左心室壁运动减弱-运动失调节段的患者中,测量了室壁瘤的绝对体积及其占左心室总体积的百分比(V An%)。研究了其与左心室功能的其他血流动力学和血管造影参数之间的统计学相关性。心脏指数和血管造影每搏量随V An%的增加而降低,但相关性较低,无统计学意义;仅对于体积为60%或更大的室壁瘤,心脏指数和每搏量持续降低。80%的病例左心室舒张末压高于正常,随V An%的增加而升高,但相关性的统计学意义较低。舒张末期容积随V An%的增加而逐渐显著增加,因此与无收缩节段的范围有关。