Toro Juan P, Patel Ankit D, Lytle Nathaniel W, Perez Sebastian, Edward Lin, Singh Arvinpal, Davis S Scott
Department of Surgery, Emory University School of Medicine, Atlanta, GA.
Surg Laparosc Endosc Percutan Tech. 2015 Aug;25(4):324-30. doi: 10.1097/SLE.0000000000000181.
Restrictive bariatric procedures reduce gastric capacity as a primary mechanism of action. Intraoperatively, surgeons observe variability in size and compliance of specimens. We hypothesized that higher gastric specimen volume or tissue compliance would respond better to restrictive procedures.
Consecutive patients undergoing laparoscopic sleeve gastrectomy between September 2012 and September 2013 were enrolled. Specimens were insufflated at graduated pressure points creating pressure volume curves, and compliance was calculated. Postoperative weight loss and a hunger scores were recorded. Correlations were determined by Spearman correlation.
Eighty-four patients consented to enrollment. Mean age, weight, and body mass index (BMI) were 45 ± 12 years, 126 ± 23 kg, and 45.4 ± 6 m/kg2, respectively. The resected specimens varied in insufflated capacity from 0.3 to 1.8 (0.71 ± 0.32) L and compliance varied from 14.3 to 85.7 (36.1 ± 14.7) cc/mm Hg. Male patients had a larger greater curvature length (GCL) (P < 0.001), staple line length (SLL) (P = 0.03), gastric volume (GV) (P = 0.002), and gastric compliance (GC) (P < 0.001). Neither GV nor GC correlated to excess body weight loss (EBWL%) as hypothesized. There was an inverse correlation between hunger score and GV (P = 0.010). The mean 1-month, 3-month, 6-month, and 12-month EBWL was 17.4%, 33.2%, 43.7%, and 54.1%, respectively. Follow-up was 71.4% at 1 month, 39.3% at 3 months, 54.8% at 6 months, and 42.9% at 12 months.
Sleeve gastrectomy specimens exhibit nearly 6-fold variability in both volume and compliance. A large GC is anticipated in male and tall subjects. These observations do not appear to be correlated to %EBWL.
限制性减肥手术以减少胃容量作为主要作用机制。在手术过程中,外科医生观察到标本的大小和顺应性存在差异。我们假设胃标本体积越大或组织顺应性越好,对限制性手术的反应就越好。
纳入2012年9月至2013年9月期间连续接受腹腔镜袖状胃切除术的患者。在不同的压力点对标本进行充气,绘制压力-容积曲线,并计算顺应性。记录术后体重减轻情况和饥饿评分。通过Spearman相关性分析确定相关性。
84例患者同意入组。平均年龄、体重和体重指数(BMI)分别为45±12岁、126±23kg和45.4±6m/kg²。切除标本的充气容量在0.3至1.8(0.71±0.32)L之间变化,顺应性在14.3至85.7(36.1±14.7)cc/mm Hg之间变化。男性患者的大弯长度(GCL)更大(P<0.001)、吻合钉线长度(SLL)更长(P=0.03)、胃容量(GV)更大(P=0.002)以及胃顺应性(GC)更高(P<0.001)。与假设相反,GV和GC均与超重体重减轻百分比(EBWL%)无关。饥饿评分与GV呈负相关(P=0.010)。1个月、3个月、6个月和12个月时的平均EBWL分别为17.4%、33.2%、43.7%和54.1%。1个月时的随访率为71.4%,3个月时为39.3%,6个月时为54.8%,12个月时为42.9%。
袖状胃切除标本的体积和顺应性变化近6倍。预计男性和高个子受试者的GC较大。这些观察结果似乎与EBWL%无关。