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首次在泪腺中发现卟啉:与哈德氏腺的相似性。

First demonstration of porphyrins in the lacrimal glands: similarity to the Harderian gland.

作者信息

Hugo J, Vokurka M, Sanitrák J, Mĕlková Z, Janousek V

机构信息

Department of Pathological Physiology, Faculty of General Medicine, Charles University, Prague, Czechoslovakia.

出版信息

Biomed Biochim Acta. 1989;48(9):K1-K4.

PMID:2619732
Abstract

The Harderian gland of rodents is the only known tissue with physiological occurrence of high concentrations of porphyrins. In this report we describe the occurrence of considerable concentrations of porphyrins in the extra-orbital and intra-orbital lacrimal glands of the male rat. Similarly as in the Harderian gland, HPLC analysis revealed protoporphyrin as being the prevalent porphyrin homologue in the lacrimal glands. The results may contribute to elucidation of the yet unknown function of the Harderian gland and its porphyrins.

摘要

啮齿动物的哈德氏腺是唯一已知在生理上会出现高浓度卟啉的组织。在本报告中,我们描述了雄性大鼠眶外和眶内泪腺中存在相当浓度的卟啉。与哈德氏腺类似,高效液相色谱分析显示原卟啉是泪腺中普遍存在的卟啉同系物。这些结果可能有助于阐明哈德氏腺及其卟啉尚未明确的功能。

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