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以弥散性血管内凝血为首发特征的原发性侵袭性曲霉病,作为非霍奇金淋巴瘤的一种表现形式。

Primary invasive aspergillosis with disseminated intravascular coagulation as a presenting feature of non-Hodgkin's lymphoma.

作者信息

Balsitis Margaret, Elgoweini Maha, Martin Sarah J, Shankland Gillian S, Paxton Jane, Bal Abhijit M

机构信息

Department of Pathology, University Hospital Crosshouse, Kilmarnock KA2 0BE, United Kingdom.

Infection Unit, University Hospital Crosshouse, Kilmarnock KA2 0BE, United Kingdom.

出版信息

Med Mycol Case Rep. 2015 Jul 2;9:15-7. doi: 10.1016/j.mmcr.2015.06.005. eCollection 2015 Sep.

Abstract

Invasive aspergillosis (IA) is a life-threatening infection. IA is usually seen in severely immunocompromised patients. However, IA as a presenting feature of non-Hodgkin's lymphoma is rare. The patient we describe had no signs or symptoms of lymphoma prior to hospital admission. A. fumigatus was isolated from respiratory tract specimens on the day of admission and fungal elements were detected on autopsy. Isolation of Aspergillus in patients with severe sepsis should trigger a search haematological malignancy.

摘要

侵袭性曲霉病(IA)是一种危及生命的感染。IA通常见于严重免疫功能低下的患者。然而,IA作为非霍奇金淋巴瘤的首发特征较为罕见。我们描述的这位患者在入院前没有淋巴瘤的体征或症状。入院当天从呼吸道标本中分离出烟曲霉,尸检时检测到真菌成分。在严重脓毒症患者中分离出曲霉菌应促使对血液系统恶性肿瘤进行排查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ad9/4506975/4aab734ffb5f/gr1.jpg

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