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首次植入或翻修心脏起搏器或植入式心律转复除颤器的无症状患者的静脉阻塞:一项回顾性单中心分析

Venous Obstruction in Asymptomatic Patients Undergoing First Implantation or Revision of a Cardiac Pacemaker or Implantable Cardioverter-Defibrillator: A Retrospective Single Center Analysis.

作者信息

Pieper C C, Weis V, Fimmers R, Rajab I, Linhart M, Schild H H, Nähle C P

机构信息

Department of Radiology, University of Bonn, Germany.

Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Germany.

出版信息

Rofo. 2015 Nov;187(11):1029-35. doi: 10.1055/s-0035-1553351. Epub 2015 Jul 22.

Abstract

PURPOSE

To investigate the incidence and possible risk factors of upper deep vein obstruction in patients both prior to first cardiac device implantation and before device revision.

MATERIALS AND METHODS

Records of asymptomatic patients undergoing contrast venography prior to implantation or revision of a cardiac device from 09/2009 to 04/2012 were reviewed. Venograms were used to determine the presence of venous obstruction. Interrelations between the incidence of venous obstruction and patient- or device-related parameters were identified using Fisher's exact test and univariate logistic regression. Multivariate logistic regression was used to identify independent predictors of venous obstruction.

RESULTS

456 patients met the inclusion criteria (330 males, 126 females, 67.8  ±  12.9 years). 100 patients underwent first implantation, and 356 patients underwent device revision (mean time since implantation 82.5  ±  75.3 months). Venous obstruction was present in 11.0 % and 30.1 % before implantation and revision, respectively. Only presence of ventricular escape rhythm was significantly related to venous occlusion (p < 0.001) prior to first implantation. Prior to revision, significant predictors were male sex (p = 0.01), time since implantation (p < 0.0001), presence of escape rhythm (p = 0.02), compromised coagulation (p = 0.02), phenprocoumon (p = 0.005), and peripheral arterial disease (p = 0.01).

CONCLUSION

Although several risk factors could be identified, reliable prediction of venous obstruction was not possible. Therefore, we advocate performing venography in all patients prior to device revision or upgrade to avoid complications. In cases of first device implantation, the risks associated with venography should be weighed against the surprisingly high rate of deep upper vein obstruction.

摘要

目的

调查首次心脏装置植入前及装置翻修前患者上腔深静脉阻塞的发生率及可能的危险因素。

材料与方法

回顾了2009年9月至2012年4月期间在植入或翻修心脏装置前接受造影剂静脉造影的无症状患者的记录。静脉造影用于确定静脉阻塞的存在。使用Fisher精确检验和单因素逻辑回归确定静脉阻塞发生率与患者或装置相关参数之间的相互关系。多因素逻辑回归用于确定静脉阻塞的独立预测因素。

结果

456例患者符合纳入标准(男性330例,女性126例,年龄67.8±12.9岁)。100例患者接受首次植入,356例患者接受装置翻修(自植入以来的平均时间为82.5±75.3个月)。植入前和翻修前静脉阻塞的发生率分别为11.0%和30.1%。首次植入前,仅室性逸搏心律与静脉闭塞显著相关(p<0.001)。翻修前,显著的预测因素为男性(p=0.01)、植入后时间(p<0.0001)、逸搏心律的存在(p=0.02)、凝血功能受损(p=0.02)、苯丙香豆素(p=0.005)和外周动脉疾病(p=0.01)。

结论

虽然可以确定几个危险因素,但无法可靠预测静脉阻塞。因此,我们主张在所有患者进行装置翻修或升级前进行静脉造影,以避免并发症。在首次装置植入的情况下,应权衡静脉造影相关风险与上腔深静脉阻塞的惊人高发生率。

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