Susla Gregory M
Gregory M. Susla is President, Washington DC Area Critical Care Society, 5301 Hines Rd, Frederick, MD 21704 (
AACN Adv Crit Care. 2015 Jul-Sep;26(3):244-51. doi: 10.1097/NCI.0000000000000098.
Continuous renal replacement therapy is frequently used to manage acute renal failure in critically ill patients. Antibiotic drugs used to treat infections in critically ill patients need to be dosed on the basis of the method of renal replacement therapy to be used, degree of residual renal function, and the sensitivity of the organism to be treated. Antibiotic dosing regimens must then be continuously monitored and adjusted according to modifications made to the renal replacement circuit and the patient's underlying condition.
连续性肾脏替代疗法常用于治疗危重症患者的急性肾衰竭。用于治疗危重症患者感染的抗生素药物，需要根据拟采用的肾脏替代疗法、残余肾功能程度以及待治疗病原体的敏感性来确定给药剂量。随后，必须根据肾脏替代回路的改变以及患者的基础病情，持续监测和调整抗生素给药方案。
