Naeije R
Bull Mem Acad R Med Belg. 1989;144(5-7):335-43; discussion 343-6.
The function of the autonomic innervation of the pulmonary vasculature remains incompletely understood. Recent studies have contributed to a better understanding of pressure-flow relationships within the pulmonary circulation in intact dog experimental models. This methodological approach has been used to show that, in normal hyperoxic or moderately hypoxic lungs, the sympathetic nervous system exerts a net vasodilatating effect, while the parasympathetic nervous system does not seem to participate to the regulation of vasomotor tone. These results underscore that research in "traditional" physiology still is implicated in ongoing progress in physiopathology and therapeutics.
肺血管系统自主神经支配的功能仍未完全明了。最近的研究有助于更好地理解完整犬实验模型肺循环内的压力-流量关系。这种方法已被用于表明,在正常高氧或中度低氧肺中,交感神经系统发挥净血管舒张作用,而副交感神经系统似乎不参与血管运动张力的调节。这些结果强调,“传统”生理学的研究仍然与病理生理学和治疗学的持续进展相关。