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基于循证医学的(肛门生殖器)硬化性苔藓(S3)指南。

Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus.

作者信息

Kirtschig G, Becker K, Günthert A, Jasaitiene D, Cooper S, Chi C-C, Kreuter A, Rall K K, Aberer W, Riechardt S, Casabona F, Powell J, Brackenbury F, Erdmann R, Lazzeri M, Barbagli G, Wojnarowska F

机构信息

Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, UK.

Institute of General Practice and Interprofessional Care, University of Tübingen, Tübingen, Germany.

出版信息

J Eur Acad Dermatol Venereol. 2015 Oct;29(10):e1-43. doi: 10.1111/jdv.13136. Epub 2015 Jul 22.

Abstract

Lichen sclerosus (LS) is an inflammatory skin disease that usually involves the anogenital area. All patients with symptoms or signs suspicious of lichen sclerosus should be seen at least once initially by a physician with a special interest in the disease in order to avoid delay in diagnosis, as early treatment may cure the disease in some and reduce or prevent scarring. The diagnosis is made clinically in most cases. Biopsies should only be performed under certain circumstances. The gold standard for treatment remains potent to very potent topical steroids; however, mild and moderate disease in boys and men may be cured by circumcision. Certain triggers should be avoided. http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html.

摘要

硬化性苔藓(LS)是一种通常累及肛门生殖器区域的炎症性皮肤病。所有有疑似硬化性苔藓症状或体征的患者最初都应至少由一位对该疾病有特殊兴趣的医生诊治一次,以避免诊断延误,因为早期治疗在某些情况下可能治愈该病,并减少或防止瘢痕形成。大多数情况下,诊断依靠临床判断。仅在某些特定情况下才进行活检。治疗的金标准仍然是强效至超强效外用类固醇;然而,男孩和男性的轻度和中度病例可通过包皮环切术治愈。应避免某些诱发因素。http://www.euroderm.org/images/stories/guidelines/2014/S3-Guideline-on-Lichen-sclerosus.pdf http://www.awmf.org/fachgesellschaften/mitgliedsgesellschaften/visitenkarte/fg/deutsche-gesellschaft-fuer-gynaekologie-und-geburtshilfe-dggg.html

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