Promm M, Rösch W H, Kirtschig G
Klinik für Kinderurologie in Kooperation mit der Universität Regensburg, Klinik St. Hedwig, Steinmetzstr. 1-3, 93049, Regensburg, Deutschland.
Medbase/santemed Gesundheitszentren AG, Frauenfeld, Schweiz.
Urologe A. 2020 Mar;59(3):271-277. doi: 10.1007/s00120-020-01140-w.
Lichen sclerosus (LS) is a chronic inflammatory disease of the skin. It mainly affects the anogenital area. More knowledge of the disease is needed to avoid delay in diagnosis as early treatment may cure the disease in some and reduce or prevent scarring. Initial treatment for girls and boys comprises the daily application of a potent cortisone ointment for 3 months. After remission the treatment should be continued long-term intermittently. If there is no complete remission in boys complete circumcision is recommended. LS usually cannot be healed but only well suppressed, and also after circumcision recurrences may occur years later. Therefore, patients have to be well informed and should be followed up long-term.
硬化性苔藓(LS)是一种皮肤慢性炎症性疾病。它主要累及肛门生殖器部位。需要更多关于该疾病的知识以避免诊断延误,因为早期治疗可能使部分患者治愈,并减少或预防瘢痕形成。女孩和男孩的初始治疗包括每日外用强效皮质类固醇软膏,持续3个月。缓解后,治疗应长期间歇性持续。如果男孩没有完全缓解,建议进行包皮环切术。LS通常无法治愈,只能得到良好控制,而且包皮环切术后数年仍可能复发。因此,必须让患者充分了解情况,并应进行长期随访。