Dawson C R, Juster R, Marx R, Daghfous M T, Ben Djerad A
Francis I. Proctor Foundation for Research in Ophthalmology and Scientific Computing Center, University of California, San Francisco 94143-0412.
Eye (Lond). 1989;3 ( Pt 2):204-9. doi: 10.1038/eye.1989.29.
Ocular infection with Chlamydia trachomatis, whether of genital or endemic trachoma origin, usually produces diffuse infiltration and swelling of the scleral limbus, grey infiltrates of the corneal limbus, and superficial extension of vessels onto the corneal limbus. In genitally transmitted C. trachomatis infections, subepithelial infiltrates have been reported as well. In classic endemic trachoma, limbal changes also include limbal follicles which resolve, leaving Herbert's peripheral pits, and an extensive vascular pannus. To evaluate the limbal changes in trachoma, follow-up studies were done in 1986-1987 in a group of 213 children originally seen between 1969-1972. Pannus formation occurred at a much earlier age than conjunctival scar formation and was an excellent predictor of later severe conjunctival scarring. The evidence from this study suggests that the mechanisms for corneal pannus formation from the limbus are quite different from those for scarring of the conjunctiva.
沙眼衣原体眼部感染，无论源于生殖道感染还是地方性沙眼，通常都会导致巩膜缘弥漫性浸润和肿胀、角膜缘灰色浸润以及血管向角膜缘的浅层延伸。在性传播的沙眼衣原体感染中，也有上皮下浸润的报道。在典型的地方性沙眼中，角膜缘变化还包括角膜缘滤泡，这些滤泡消退后会留下赫伯特周边凹坑，以及广泛的血管翳。为了评估沙眼中角膜缘的变化，1986 - 1987年对一组1969 - 1972年间首次就诊的213名儿童进行了随访研究。血管翳形成的年龄比结膜瘢痕形成的年龄要早得多，并且是后期严重结膜瘢痕形成的一个很好的预测指标。这项研究的证据表明，角膜缘形成角膜血管翳的机制与结膜瘢痕形成的机制有很大不同。
