Venditti Alessandro, Frezza Claudio, Serafini Mauro, Bianco Armandodoriano
a Dipartimento di Chimica , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.
b Dipartimento di Biologia Ambientale , Sapienza Università di Roma , P.le A. Moro 5, 00185 Roma , Italy.
Nat Prod Res. 2016;30(3):327-31. doi: 10.1080/14786419.2015.1060230. Epub 2015 Jul 24.
In this study, we report the first phytochemical analysis of polar fraction of Pedicularis kerneri Dalla Torre growing in Dolomites, Italy. Several iridoid glucosides were isolated, namely aucubin (1), monomelittoside (2), plantarenaloside (3), euphroside (4), mussaenosidic acid (5) and 8-epiloganic acid (6), showing a composition in accordance with previous study on this genus. The studied samples, collected from Dolomites, presented a chemotype already recognised in species from North America, characterised by euphroside (4) and aucubin (1) as main components, but the main character was the presence of monomelittoside (2) never reported in this genus. The identification of verbascoside (7), leucosceptoside A (9) and echinacoside (10) complete the systematic framing of this species since is ascertained the co-occurrence of phenylethanoid glycosides with iridoids in Lamiales species.
在本研究中，我们报告了对生长于意大利多洛米蒂山脉的克氏马先蒿极地部分的首次植物化学分析。分离出了几种环烯醚萜苷，即桃叶珊瑚苷（1）、单蜜茱萸苷（2）、车前肾苷（3）、喜普诺苷（4）、穆萨依酸（5）和8 - 表马钱子酸（6），其成分与此前对该属的研究一致。从多洛米蒂山脉采集的研究样本呈现出一种在北美物种中已被识别的化学型，其特征是以喜普诺苷（4）和桃叶珊瑚苷（1）为主要成分，但主要特点是存在该属中从未报道过的单蜜茱萸苷（2）。毛蕊花糖苷（7）、白花败酱苷A（9）和紫锥菊苷（10）的鉴定完善了该物种的系统框架，因为已确定在唇形目物种中苯乙醇苷与环烯醚萜同时存在。
