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颈椎椎板切除融合术后的C5麻痹:椎板切除宽度重要吗?

C5 palsy after cervical laminectomy and fusion: does width of laminectomy matter?

作者信息

Klement Mitchell R, Kleeman Lindsay T, Blizzard Daniel J, Gallizzi Michael A, Eure Megan, Brown Christopher R

机构信息

Department of Orthopaedic Surgery, Duke University Medical Center, Box 3000, Durham, NC 27710, USA.

Department of Orthopaedic Surgery, Duke University Medical Center, Box 3000, Durham, NC 27710, USA.

出版信息

Spine J. 2016 Apr;16(4):462-7. doi: 10.1016/j.spinee.2015.07.437. Epub 2015 Jul 21.

Abstract

BACKGROUND CONTEXT

A common complication of cervical laminectomy and fusion with instrumentation (CLFI) is development of postoperative C5 nerve palsy. A proposed etiology is excess nerve tension from posterior drift of the spinal cord after decompression. We hypothesize that laminectomy width will be significantly increased in patients with C5 palsy and will correlate with palsy severity.

PURPOSE

The purposes of this study were to evaluate laminectomy width as a risk factor for C5 palsy and to assess correlation with palsy severity.

STUDY DESIGN/SETTING: This is a retrospective, single-institution clinical study.

PATIENT SAMPLE

Patient population included all patients with cervical spondylotic myelopathy who underwent CLFI between 2007 and 2014 by a single surgeon. Patients who underwent CLFI for trauma, infection, or tumor or had previous or circumferential cervical surgery were excluded. All patients with a new C5 palsy received a postoperative magnetic resonance imaging. An additional computed tomography (CT) scan was ordered to assess hardware. All control patients received a CT scan at 6 months postoperatively to evaluate fusion.

OUTCOME MEASURES

The association between width of laminectomy and development of postopeative C5 palsy was measured.

METHODS

Patient comorbidities including obesity, smoking history, and diabetes were recorded in addition to preopertaive and postoperative deltoid and biceps motor strength. Sagittal alignment was measured with C2-C7 Cobb angle preopertaive and postoperative radiographs. The width of laminectomy was measured in a blinded fashion on the postoperative CT scan by two observers.

RESULTS

Seventeen patients with C5 nerve palsy and 12 controls were identified. There were no baseline differences in age, sex, diabetes, smoking history, number of surgical levels, or sagittal alignment. Body mass index was significantly higher in the control cohort. There was no significant increase in the C3-C7 laminectomy width in patients with postoperative C5 palsy. The width of laminectomy measurments were highly similar between the two observers. There was no correlation between laminectomy width and palsy severity.

CONCLUSIONS

This is the largest series of C5 palsies after laminectomy documented with CT imaging. Laminectomy width was not associated with an increased risk of postoperative C5 palsy at any level. Reduction in laminectomy width may not reduce rate of postoperative nerve palsy.

摘要

背景

颈椎椎板切除减压融合内固定术(CLFI)的一种常见并发症是术后C5神经麻痹。一种推测的病因是减压后脊髓向后移位导致神经张力过大。我们假设C5麻痹患者的椎板切除宽度会显著增加,且与麻痹严重程度相关。

目的

本研究的目的是评估椎板切除宽度作为C5麻痹的危险因素,并评估其与麻痹严重程度的相关性。

研究设计/地点:这是一项回顾性单机构临床研究。

患者样本

患者群体包括2007年至2014年间由同一位外科医生进行CLFI的所有脊髓型颈椎病患者。因创伤、感染或肿瘤接受CLFI或曾接受过颈椎前路或后路手术的患者被排除。所有新发C5麻痹患者均接受术后磁共振成像检查。另外还进行了计算机断层扫描(CT)以评估内固定情况。所有对照患者在术后6个月接受CT扫描以评估融合情况。

观察指标

测量椎板切除宽度与术后C5麻痹发生之间的关联。

方法

记录患者的合并症,包括肥胖、吸烟史和糖尿病,以及术前和术后三角肌和肱二头肌的肌力。术前和术后X线片通过C2-C7 Cobb角测量矢状位对线情况。由两名观察者在术后CT扫描上以盲法测量椎板切除宽度。

结果

确定了17例C5神经麻痹患者和12例对照。在年龄、性别、糖尿病、吸烟史、手术节段数或矢状位对线方面,两组之间无基线差异。对照组的体重指数显著更高。术后C5麻痹患者的C3-C7椎板切除宽度无显著增加。两名观察者测量的椎板切除宽度高度相似。椎板切除宽度与麻痹严重程度之间无相关性。

结论

这是有CT成像记录的最大系列颈椎椎板切除术后C5麻痹病例。任何节段的椎板切除宽度均与术后C5麻痹风险增加无关。减小椎板切除宽度可能无法降低术后神经麻痹的发生率。

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