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有限椎板切除术和椎间孔减压联合内固定治疗多节段脊髓型颈椎病:能否有效改善神经功能并预防C5麻痹?

Limited laminectomy and foraminal decompression combined with internal fixation for treating multi-segment cervical spondylotic myelopathy: Does it effectively improve neurological function and prevent C5 palsy?

作者信息

Zhao Yue-Jiang, Cheng Cai, Chen Han-Wen, Li Min, Wang Lu, Guo Zhi-Yuan

机构信息

Department of Orthopaedics, Cangzhou Central Hospital, Cangzhou, China.

出版信息

Medicine (Baltimore). 2018 Nov;97(47):e13327. doi: 10.1097/MD.0000000000013327.

Abstract

Laminectomy is an effective surgical treatment for multi-segment cervical spondylotic myelopathy (M-CSM) but usually results in C5 palsy. Some surgical techniques to restore the spinal sequence, increase the intervertebral foramen diameter, and limit the spinal cord drift distance have been proposed; however, it is unclear whether these procedures can avoid this complication.To investigate the clinical efficacy of limited laminectomy and foraminal decompression with fixation (LLFDF) for improving neurological recovery and preventing C5 palsy.A total of 71 patients with M-CSM were retrospectively analyzed. Thirty-nine of them were treated with LLFDF (group A) and 32 with normal laminectomy with fixation (NLF; group B) after 3 months of formal conservative treatment. Pre- and postoperative neurological function, spinal cord drift distance, cervical curvature index (CCI), and number of C5 palsy cases were recorded and analyzed.There was no significant intergroup difference in the surgical time or intraoperative blood loss (P >.05). The laminectomy widths in groups A and B were 16.7 ± 2.6 mm and 21.8 ± 2.9 mm, respectively (P <.01), while the spinal cord drift distances were 2.3 ± 0.4 mm and 3.6 ± 0.7 mm, respectively (P <.01). The mean Japanese Orthopedic Association score of both groups increased significantly after surgery (P <.01), and no significant difference was noted at any observation time points (P >.05). Both groups demonstrated significant CCI improvements after surgery compared with those before surgery (P <.01). There were 2 cases of C5 palsy in group A (5.1%) and 8 cases in group B (25.0%), and the difference was significant (P <.05).LLFDF can relieve spinal compression and considerably promote neurological recovery. Moreover, it restricts excessive spinal cord back drifting and decreases the incidence of C5 palsy.

摘要

椎板切除术是治疗多节段脊髓型颈椎病(M-CSM)的一种有效手术方法,但通常会导致C5麻痹。已经提出了一些恢复脊柱序列、增加椎间孔直径和限制脊髓漂移距离的手术技术;然而,这些手术是否能够避免这种并发症尚不清楚。为了研究有限椎板切除术联合椎间孔减压并固定(LLFDF)在改善神经功能恢复和预防C5麻痹方面的临床疗效。对71例M-CSM患者进行了回顾性分析。在经过3个月正规保守治疗后,其中39例接受LLFDF治疗(A组),32例接受常规椎板切除术并固定(NLF;B组)。记录并分析术前和术后的神经功能、脊髓漂移距离、颈椎曲度指数(CCI)以及C5麻痹病例数。手术时间和术中出血量在组间无显著差异(P>0.05)。A组和B组的椎板切除宽度分别为16.7±2.6mm和21.8±2.9mm(P<0.01),而脊髓漂移距离分别为2.3±0.4mm和3.6±0.7mm(P<0.01)。两组术后日本骨科协会平均评分均显著提高(P<0.01),在任何观察时间点均无显著差异(P>0.05)。与术前相比,两组术后CCI均有显著改善(P<0.01)。A组有2例C5麻痹(5.1%),B组有8例(25.0%),差异有统计学意义(P<0.05)。LLFDF可以缓解脊髓压迫并显著促进神经功能恢复。此外,它限制了脊髓过度向后漂移并降低了C5麻痹的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c858/6392563/34c3f6002da1/medi-97-e13327-g002.jpg

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