Kenig Jakub, Zychiewicz Beata, Olszewska Urszula, Barczynski Marcin, Nowak Wojciech
3rd Department of General Surgery, Jagiellonian Univeristy Medical College, Pradnicka str. 35-37, 31-202 Krakow, Poland.
Arch Gerontol Geriatr. 2015 Nov-Dec;61(3):437-42. doi: 10.1016/j.archger.2015.06.018. Epub 2015 Jul 6.
The literature on geriatric assessment in emergency admitted patients is scarce, particularly there are no studies regarding the efficacy of frailty screening tests among patients qualified for emergency abdominal surgery. Therefore, the aim of this study was to compare the diagnostic accuracy of six screening instruments in this group of patients.
The diagnostic accuracy of the Vulnerable Elderly Survey (VES-13), Triage Risk Screening Tool (TRST), Geriatric-8 (G8), Groningen Frailty Index (GFI), Rockwood, Balducci score was evaluated in a prospective group of 184 consecutive patients ≥65 years of age. Outcome measure was sensitivity, specificity, positive and negative predictive values of these tests in prediciting 30-day postoperative outcome.
Patients mean age was 76.9±5.8 (65-100) years. The prevalence of frailty, as diagnosed by screening methods, was: 50-79.9% (Balducci/Rockwood-G8). Multivariate analyses have identified all screening tests apart from Rockwood and TRST as independent factors that predict postoperative outcome. The sensitivity and negative predictive value in case of postoperative mortality were 60-91% (Rockwood-VES-13) and 30-93% (GFI-VES13). In case of postoperative morbidity they were 52-85% (Rockwood-VES-13 and G8) and 44-70% (Rockwood-VES-13), respectively.
Considering these results, it is possible to perform safely and efficiently screening test for frailty in older patients qualified for emergency abdominal surgery. The VES-13 was the best screening instrument; it had the highest sensitivity and negative predictive value both for the postoperative mortality and morbidity. This instrument may offer physicians additional information that can be used in the postoperative optimisation of the treatment of these high-risk group of patients.
关于急诊入院患者老年评估的文献较少,尤其是对于符合急诊腹部手术条件的患者,尚无关于衰弱筛查测试有效性的研究。因此,本研究的目的是比较六种筛查工具在该组患者中的诊断准确性。
对连续184例年龄≥65岁的患者进行前瞻性研究,评估脆弱老年人调查(VES-13)、分诊风险筛查工具(TRST)、老年8项(G8)、格罗宁根衰弱指数(GFI)、罗克伍德指数、巴尔杜奇评分的诊断准确性。结局指标是这些测试预测术后30天结局的敏感性、特异性、阳性和阴性预测值。
患者平均年龄为76.9±5.8(65-100)岁。通过筛查方法诊断的衰弱患病率为:50-79.9%(巴尔杜奇/罗克伍德-G8)。多变量分析已确定,除罗克伍德指数和TRST外,所有筛查测试都是预测术后结局的独立因素。术后死亡率的敏感性和阴性预测值分别为60-91%(罗克伍德-VES-13)和30-93%(GFI-VES13)。术后发病率的敏感性和阴性预测值分别为52-85%(罗克伍德-VES-13和G8)和44-70%(罗克伍德-VES-13)。
考虑到这些结果,对于符合急诊腹部手术条件的老年患者,可以安全有效地进行衰弱筛查测试。VES-13是最佳筛查工具;它对术后死亡率和发病率均具有最高的敏感性和阴性预测值。该工具可为医生提供额外信息,可用于对这些高危患者进行术后治疗优化。