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卵巢门细胞增生类似于支持细胞瘤:显微镜下的肿瘤还是非肿瘤性残余?

Ovarian hilar proliferations resembling Sertoli cell tumours: microscopic neoplasms or non-neoplastic remnants?

机构信息

Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK.

Department of Pathology and Laboratory Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.

出版信息

Histopathology. 2016 Mar;68(4):596-602. doi: 10.1111/his.12784. Epub 2015 Sep 4.

Abstract

AIMS

To describe four cases of incidentally detected microscopic ovarian hilar Sertoli cell proliferation, a phenomenon that, as far as we are aware, has not been previously reported, and to discuss the differential diagnosis of these lesions.

METHODS AND RESULTS

The proliferations occurred in women aged 35-62 years, and were composed of solid and hollow tubules that were morphologically and immunohistochemically in keeping with Sertoli cells. Two cases were bilateral.

CONCLUSIONS

We feel that these uncommon proliferations are likely to represent non-neoplastic embryological remnants rather than hilar Sertoli cell tumours.

摘要

目的

描述 4 例偶然发现的卵巢门部微小型 Sertoli 细胞增生,据我们所知,该现象此前尚未有报道,并讨论这些病变的鉴别诊断。

方法和结果

增生发生于 35-62 岁女性,由实性和腔隙性小管组成,形态学和免疫组织化学均符合 Sertoli 细胞。其中 2 例为双侧性。

结论

我们认为这些不常见的增生可能代表非肿瘤性胚胎性残留,而非卵巢门部 Sertoli 细胞瘤。

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