Young R H, Scully R E
Int J Gynecol Pathol. 1984;2(4):349-63. doi: 10.1097/00004347-198404000-00003.
Ten Sertoli cell tumors of the ovary, which occurred in patients from 2 to 62 years of age (average 38 years), are reported. Two prepubertal patients presented because of isosexual precocity, and there was evidence of estrogenic stimulation of the endometrium in two postmenopausal women. The tumors were all Stage Ia and ranged from 0.8 to 17 cm in diameter. On microscopic examination five of them contained tubules that were predominantly hollow, and five, tubules that were predominantly solid. Two of the neoplasms in the latter group were of the lipid-rich type. Seven tumors were well differentiated, two were of intermediate differentiation, and one was poorly differentiated. The last tumor, which metastasized widely and was rapidly fatal, was the only clinically malignant tumor in the series.
本文报道了10例卵巢支持细胞瘤，患者年龄在2岁至62岁之间（平均38岁）。两名青春期前患者因同性性早熟就诊，两名绝经后女性有子宫内膜受雌激素刺激的证据。所有肿瘤均为Ia期，直径在0.8至17厘米之间。显微镜检查显示，其中5例肿瘤含有以空心为主的小管，5例含有以实性为主的小管。后一组中的2例肿瘤为富含脂质型。7例肿瘤分化良好，2例为中等分化，1例为低分化。最后1例肿瘤发生广泛转移且迅速致命，是该系列中唯一的临床恶性肿瘤。
