Andersen P E, Midtgaard A, Brenøe A S, Elle B, Duvnjak S
Department of Interventional Radiology, Odense University Hospital, Odense, Denmark -
J Cardiovasc Surg (Torino). 2015 Dec;56(6):877-81. Epub 2015 Jul 27.
The aim of the study was to assess the early clinical experience with the Zilver Vena stent in treating patients with malignant superior vena cava syndrome.
Demographic, procedural, and follow-up data of 12 patients (seven women; mean age 69 years) treated for superior vena cava syndrome with in all 21 Zilver Vena stents between March 2012 and October 2013 were retrospectively reviewed. All cavographies and contrast enhanced CT related to the treatment and during follow-up were evaluated and the patients had clinical follow-up until dead. They were all in terminal state at the time of stent deployment.
All patients had superior vena cava obstruction and clinical superior vena cava syndrome caused by malignant expansive mediastinal disease (eight patients non-small cell lung cancer and four small cell lung cancer). The technical success with deployment of the stents in the intended position was 75%. Good clinical effect with resolution of superior vena cava syndrome was achieved in 11 of the 12 patients (92%).
The Zilver Vena stent appeared to be safe, easy to deploy, and showed good clinical outcome. The high radial force of the stent might be of advantage in these patients with expanding masses around the superior vena cava.
本研究旨在评估Zilver Vena支架治疗恶性上腔静脉综合征患者的早期临床经验。
回顾性分析2012年3月至2013年10月期间，12例（7例女性；平均年龄69岁）接受上腔静脉综合征治疗并植入21枚Zilver Vena支架患者的人口统计学、手术及随访数据。评估所有与治疗及随访期间相关的腔静脉造影和增强CT，并对患者进行临床随访直至死亡。在植入支架时，他们均处于终末期。
所有患者均有上腔静脉阻塞及由恶性扩展性纵隔疾病导致的临床性上腔静脉综合征（8例非小细胞肺癌，4例小细胞肺癌）。支架在预期位置成功植入的技术成功率为75%。12例患者中有11例（92%）上腔静脉综合征得到缓解，临床效果良好。
Zilver Vena支架似乎安全、易于植入，且临床效果良好。支架的高径向力可能对这些上腔静脉周围有肿块的患者有益。
