具有50%量子产率的二氧化硅壳层和嵌段共聚物封装的红色发射聚集诱导发光纳米颗粒用于双光子激发血管成像。
Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging.
作者信息
Geng Junlong, Goh Chi Ching, Qin Wei, Liu Rongrong, Tomczak Nikodem, Ng Lai Guan, Tang Ben Zhong, Liu Bin
机构信息
Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore 117585.
出版信息
Chem Commun (Camb). 2015 Sep 7;51(69):13416-9. doi: 10.1039/c5cc03603h.
A polymer and silica co-protection strategy has been developed to encapsulate organic fluorogens with aggregation-induced emission and charge transfer characteristics into small nanoparticles (NPs). The co-pretected NPs show bright red fluorescence (50% quantum yield) with a large two-photon action cross-section (450 GM at 840 nm), which have been sucessfully used for two-photon fluorescence imaging of vasculature of the mouse tibial muscle.
一种聚合物和二氧化硅共保护策略已被开发出来，用于将具有聚集诱导发光和电荷转移特性的有机荧光团封装到小纳米颗粒（NPs）中。这种共保护的纳米颗粒显示出明亮的红色荧光（量子产率为50%），具有较大的双光子作用截面（在840nm处为450 GM），已成功用于小鼠胫骨肌肉血管的双光子荧光成像。
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