低危非精原细胞瘤性生殖细胞肿瘤的化疗：当前概念与争议
Chemotherapy for Good-Risk Nonseminomatous Germ Cell Tumors: Current Concepts and Controversies.
作者信息
In Gino, Dorff Tanya
机构信息
Division of Medical Oncology, USC Keck School of Medicine, USC Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA.
Division of Medical Oncology, USC Keck School of Medicine, USC Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA.
出版信息
Urol Clin North Am. 2015 Aug;42(3):347-57. doi: 10.1016/j.ucl.2015.04.009.
Abstract
The rate of diagnosis of germ cell tumors has remained fairly constant. By the International Germ Cell Cancer Consensus Classification, roughly 60% of all metastatic germ cell tumors are classified as good risk. This group of patients has an excellent prognosis, with greater than 90% expectation of cure. Treatment standards have not changed much in recent years. This article focuses on key concepts in the development of the currently accepted first-line regimens and addresses some evolving areas of interest, if not controversy.
摘要
生殖细胞肿瘤的诊断率一直相当稳定。根据国际生殖细胞癌共识分类，所有转移性生殖细胞肿瘤中约60%被归类为低风险。这组患者预后良好，治愈率超过90%。近年来治疗标准变化不大。本文重点介绍目前被接受的一线治疗方案制定中的关键概念，并探讨一些即便存在争议但仍在不断发展的关注领域。
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